Protein Alignment Trm7-32 and FTSJ1

DIOPT Version :10

• Sequence 1: NP_650590.1
• Gene: Trm7-32 / 42056
• FlyBaseID: FBgn0038471
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_001428126.1
• Gene: FTSJ1 / 24140
• HGNCID: 13254
• Length: 337
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 154/293 - (52%)
• Similarity: 192/293 - (65%)
• Gaps: 43/293 - (14%)

  Fly     1 MGKTSKDKRDIYYRQAKDEGWRARSAFKLLHVDEAYGILNGVQRAVDLCAAPGSWSQVLSRKLYD 65
            ||:|||||||:|||.||:.|||||||||||.:|:.:.:..||.|||||||||||||||||:|:
Human     1 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDKEFQLFQGVTRAVDLCAAPGSWSQVLSQKI-- 63

  Fly    66 TCETDDEKSAVKIIAVDLQAMAPIRGILQLQGDITKQSTAEAIIGHFGGNEKAQLVVCDGAPDVT 130
                 ..:.:..::|||||||||:.|::|:|||||:.|||:.||.||.|. .|.|||||||||||
Human    64 -----GGQGSGHVVAVDLQAMAPLPGVVQIQGDITQLSTAKEIIQHFKGC-PADLVVCDGAPDVT 122

  Fly   131 GVHEMDEYMQHQLLVAALSIATCVLETGGTFVAKIFKGNATSLLSSQMQIFFKKFDIYKPPSSRP 195
            |:|::|||||.|||:|||:|||.||:.||.||||||:|...:||.||:|:||......||.|||.
Human   123 GLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAKPRSSRN 187

  Fly   196 SSIEAFVVCSDFCLPEGYIPQVINPARD-----DIRLLAQKTGSEVNRRLVPFIACGDLNGLSDP 255
            ||||||.||..:..|||:||.:..|..|     |...|...|     |.:|||:.||||:.
Human   188 SSIEAFAVCQGYDPPEGFIPDLSKPLLDHSYDPDFNQLDGPT-----RIIVPFVTCGDLSS---- 243

  Fly   256 EEGKTSSSDESKSNLEYVYDAVMDDASYPLEFK 288
                              ||:   |.||||:.:
Human   244 ------------------YDS---DRSYPLDLE 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trm7-32	NP_650590.1	RlmE	1..207	CDD:440062	129/205 (63%)
FTSJ1	NP_001428126.1	Required for binding to WDR6. /evidence=ECO:0000269|PubMed:32558197	221..240		8/23 (35%)