Protein Alignment Adsl and adsl-1

DIOPT Version :10

• Sequence 1: NP_650586.2
• Gene: Adsl / 42051
• FlyBaseID: FBgn0038467
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_492049.1
• Gene: adsl-1 / 172466
• WormBaseID: WBGene00011064
• Length: 478
• Species: Caenorhabditis elegans
• Alignment Length: 485
• Identity: 216/485 - (44%)
• Similarity: 307/485 - (63%)
• Gaps: 11/485 - (2%)

  Fly     1 MASNYEGYKSPLSTRYA-SKEMQFLFSDQNKFSTWRRLWVWLAKAESRLGL-EISDAQIAEMELQ 63
            |||. :.::|.|||||. :..:..:.|:.||.:.||:||:|||:||..||| :::...|.||:..
 Worm     1 MASE-DKFESVLSTRYCKNSPLVSILSETNKATLWRQLWIWLAEAEKELGLKQVTQDAIDEMKSN 64

  Fly    64 ISNIDFEAAAAEERLTRHDVMAHVHVFAKQCPSAAPVIHLGATSCYVGDNTDLIVLRDALKLLLP 128
            ....|:....:|||..:||||||.|.|.|.||:||.:||||||||:|.||.|||..||::..:|.
 Worm    65 RDVFDWPFIRSEERKLKHDVMAHNHAFGKLCPTAAGIIHLGATSCFVQDNADLIAYRDSIDHILK 129

  Fly   129 RVASVIARLSQFAQSYKDQPTLGFTHLQPAQLTTVGKRACLWIQDLIMDERALSRCLEDLRFRGV 193
            |.|:||.||:.|:...|:..|:|.||.|.|.|.|||||..||.|:|:|..::||...:.:||||:
 Worm   130 RFATVIDRLAAFSLKNKEVVTVGRTHYQTASLVTVGKRGVLWAQELLMAFQSLSEFRDKMRFRGI 194

  Fly   194 KGTTGTQASFLQLFNGDGEKVKQLDQLVTELAGFKKAYAVTGQTYSRKVDVEIVAALASLGTTIH 258
            ||.||||.|||.||.||..||:.||:|||:.|.|...:.:|||||||:.|.::|.:|:.||....
 Worm   195 KGATGTQDSFLTLFAGDESKVEALDELVTKKANFSNRFLITGQTYSRQQDSQLVFSLSLLGAAAK 259

  Fly   259 KMCSDLRILASRKELEEPFESTQIGSSAMPYKRNPMRSERCCALARHLITLFSSAANTHATQWLE 323
            |:|:|:|:|.:..||.||||..||||||||||:|||:|||||||:|.||.....|....|.|.||
 Worm   260 KVCTDIRVLQAFGELLEPFEKDQIGSSAMPYKKNPMKSERCCALSRKLINAPQEALTILADQGLE 324

  Fly   324 RTLDDSANRRLTLSEAFLAADAALLTLLNISQGLVVYPKVIERHISQELPFMSTENIIMAMVKAG 388
            |||||||.||:.:.:..|.|:|.|.||.||.:||.|....:::.:..|:.|:..|..:|.:.:.|
 Worm   325 RTLDDSAGRRMLIPDVLLTAEALLTTLQNIFEGLSVQTDNVKKIVEDEIAFLGLEKAMMMLTEEG 389

  Fly   389 GDRQVCHEKIRVLSQEAGAQVKQHGKDNDLVVR-VRKDPYFSPILEQLDTILDAK-TFTGRASDQ 451
            .|||..|..||..:.||    ||......:.:| ...||:|..:.:::..:::.. .||||...|
 Worm   390 VDRQQAHAVIRKTALEA----KQLQATQKVDIRQTMADPFFDSVRDRVVGLVNNPINFTGRCVSQ 450

  Fly   452 VGEFVKEEVEPVLARYSEALKNVQDVKLNI 481
            ...|:.:|::|.:.:|.:  |:..:|:|::
 Worm   451 TESFIAKELKPTIDKYLD--KSAGNVQLDV 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adsl	NP_650586.2	Adenylsuccinate_lyase_2	12..447	CDD:176471	202/438 (46%)
adsl-1	NP_492049.1	Adenylsuccinate_lyase_2	11..446	CDD:176471	202/438 (46%)