Protein Alignment abd-A and HOXD4

DIOPT Version :10

• Sequence 1: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 88/296 - (29%)
• Similarity: 104/296 - (35%)
• Gaps: 118/296 - (39%)

  Fly   290 SRYTDTVMNSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIGVD----------SLGNAC 344
            |:|.|......:..........|.|.:|             ..||.|.|          ..|.
Human    10 SKYVDPKFPPCEEYLQGGYLGEQGADYY-------------GGGAQGADFQPPGLYPRPDFGE-- 59

  Fly   345 TQPASGVMPGAGGA----------GGAG-----------------IADLPR-------------- 368
             ||..|..||.|.|          ||.|                 .|.||.
Human    60 -QPFGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDPKQPPS 123

  Fly   369 ----------YPWMTLTDWMGSPFERVVCGDFNGPN--GCPRRRGRQTYTRFQTLELEKEFHFNH 421
                      ||||          ::|.....| ||  |...:|.|..|||.|.||||||||||.
Human   124 GTALKQPAVVYPWM----------KKVHVNSVN-PNYTGGEPKRSRTAYTRQQVLELEKEFHFNR 177

  Fly   422 YLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDREEQEKMKAQETMKSA 486
            ||||||||||||.|||:||||||||||||||.||:             .:....|.::..:..|:
Human   178 YLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKD-------------HKLPNTKGRSSSSSSSS 229

  Fly   487 QQNKQVQQQQQQQQQQQQQQQQQHQQQQQQPQDHHS 522
            ..:..|...               |..|...:|||:
Human   230 SCSSSVAPS---------------QHLQPMAKDHHT 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeodomain	399..455	CDD:459649	45/55 (82%)
		Abdominal-A	456..478	CDD:403567	1/21 (5%)
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		21/111 (19%)
		Antp-type hexapeptide	133..138		4/14 (29%)
		Homeodomain	155..211	CDD:459649	45/55 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		8/67 (12%)