Protein Alignment abd-A and HOXD1

DIOPT Version :10

• Sequence 1: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_078777.1
• Gene: HOXD1 / 3231
• HGNCID: 5132
• Length: 328
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 84/280 - (30%)
• Similarity: 114/280 - (40%)
• Gaps: 49/280 - (17%)

  Fly   194 GNSQAGDSSC--------SPSPSASGSSSLHRSLNDNSPGSAS---ASASASAASSVAAAAAAAA 247
            ||......||        ||||.|:.:       ..:.|..|:   |..:...|....||.||||
Human    44 GNGDGAFVSCLPLAAARPSPSPPAAPA-------RPSVPPPAAPQYAQCTLEGAYEPGAAPAAAA 101

  Fly   248 AAASSSFAIPTSKMYPYVSNHPS-SHGGLSGMAGFTGLEDKSCSRY-TDTVMNSYQSMSVPASAS 310
            ..|.          |.::.:.|: ...|:.|.|...|   .|...| |..|.:...|..:  |..
Human   102 GGAD----------YGFLGSGPAYDFPGVLGRAADDG---GSHVHYATSAVFSGGGSFLL--SGQ 151

  Fly   311 AQFAQFYQHATAAASAVSAASA--GAIGVDSLGNACTQPASGVMPGAGGAGGAGIADLPRYPWMT 373
            ..:|.|.:.....|...::|..  ||....|       ||.|..|.:........|....:.||.
Human   152 VDYAAFGEPGPFPACLKASADGHPGAFQTAS-------PAPGTYPKSVSPASGLPAAFSTFEWMK 209

  Fly   374 LTDWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLT 438
            :   ..:..::....::...:  |....|..::..|..|||||||||.||||.||||||:.|.|.
Human   210 V---KRNASKKGKLAEYGAAS--PSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLN 269

  Fly   439 ERQIKIWFQNRRMKLKKELR 458
            :.|:||||||||||.||..|
Human   270 DTQVKIWFQNRRMKQKKRER 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeodomain	399..455	CDD:459649	34/55 (62%)
		Abdominal-A	456..478	CDD:403567	1/3 (33%)
HOXD1	NP_078777.1	Antp-type hexapeptide	204..209		1/4 (25%)
		Homeodomain	233..286	CDD:459649	34/52 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..328