Protein Alignment Gyc89Db and gucy2ca

DIOPT Version :10

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_073799927.1
• Gene: gucy2ca / 572052
• ZFINID: ZDB-GENE-091118-67
• Length: 1071
• Species: Danio rerio
• Alignment Length: 745
• Identity: 171/745 - (22%)
• Similarity: 275/745 - (36%)
• Gaps: 200/745 - (26%)

  Fly    34 QSFKTHQIYPDKLMPDFAAALSASTGESFDFCMNFFGRCFVRFFSNFGYDKM------------I 86
            |..|..|...|.:.|.|..             |:|:|        ..||.|:            :
Zfish   336 QRIKQQQGLSDNIDPPFRN-------------MSFYG--------IGGYYKLDSSGDRDLNLSVV 379

  Fly    87 RSTGRYFCDFLQSIDNIHVQMRFTYPKMKSPSMQLTNMDDDGAVILYRSGRTGMSKYLIGQMTEV 151
            .:||.|....|.|.|   .....|..|..||.:......      |.|...|||      ::.|:
Zfish   380 YTTGSYKYRTLFSFD---TSQNRTKVKDSSPDLPWDRSQ------LPRDKHTGM------EIQEI 429

  Fly   152 AKEFYGLDMT-----AYVLESQNDICGGTAGPIKLTEGPLTVIVKYRLDFDNRDYMAKRVNVIAH 211
            .....||.:.     |::|..||                      .|:.||.:.:        :|
Zfish   430 MMIVLGLSVVLATVIAFILYRQN----------------------RRVRFDQKKW--------SH 464

  Fly   212 PSQLKMPSVDLNVFLELFPFTIVLDHDMKITLAGEKIVETWILHNPGVNPKTFIGSHILERFKCR 276
            .|...:..:|..   |....::.:|.|.|    |:   .:.::.....:.|..|... |......
Zfish   465 ISSSLITPLDDK---ERNYISLTIDEDKK----GD---NSSLIRKGRYDKKPVILKE-LRNTDGN 518

  Fly   277 RPKDTQIQWETILQM---------RTVLFE------FELIRTGHNRAAYDAALNF------DFE- 319
            ...|.:|:...:|::         .||.|:      ||....|..|...|..:::      |.|
Zfish   519 FTDDQRIELNALLRIDYYNLTKFYGTVRFDCGVFGVFEFCERGSLRYVLDDKISYPDASFMDLEF 583

  Fly   320 ----NFDEASSLNEAQAMALASAKEFSAENAKEEAAAAATSKD-----------EIDPATGQRRH 369
                .:|.|..::...:..:.......:.|...:........|           ::..|....|
Zfish   584 RISVMYDIAKGMSYLHSSNVGVHGRLKSTNCVVDNRMVVKITDFGCNTILSPGKDLWTAPEHMR- 647

  Fly   370 SVGLRSILLKGQMFYIKDVDSLIFL---------CSPLIENL---DELHGIGLYLNDLNPHGLSR 422
               :..|..||.::....:...|.|         ||.:.|.|   ....|..::..||:..|:..
Zfish   648 ---VEGISQKGDVYSFAIISQEIILRKSPFHTSCCSDMAEKLYLVQYPRGPNVFRPDLSFEGVGE 709

  Fly   423 E------LVMAGWQ---------------------------HCSKLEIMFEKEEQRSDELEKSLE 454
            .      |:.:.|:                           :.|.::.:..:.:..|..||..:|
Zfish   710 TEAELFVLIKSCWEEDPEKRPDFKRIEGALGKIFSNLHNQANASYMDNLIRRLQMYSRNLEHLVE 774

  Fly   455 ----LADSWKRQGDELLYSMIPRPIAERMRKSEEHVCQSFEEVSVIFIEVMNIYDSGSNNI---Q 512
                |..:.:.:.|:|.:.::|.|:...::::.....:.::||::.|.:::     |...|   .
Zfish   775 ERTALYKAERDRADQLNFMLLPGPVVRSLKETGRVEPELYDEVTIYFSDIV-----GFTTICHHS 834

  Fly   513 DAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN-PLHAEHACDLALRV---MK 573
            ..|:.|..||.::...|..:....||||||:|..||..||.|..| ..||...|.:||.:   |.
Zfish   835 TPMEVVDMLNDIYKNFDSILDHHDVYKVETIGDAYMVASGLPRCNGNRHAVDICLMALDILEFMG 899

  Fly   574 KVKAHALPGVA--IRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASRMESSSDPWMIQLSNYTAL 636
            ..:...|||:.  ||:||:|||..|||||.|:||||||||||||||||||:..|..|.:|..|..
Zfish   900 TFQLRHLPGIPLWIRIGIHSGPCAAGVVGNKMPRYCLFGDTVNTASRMESTGLPLRIHVSESTIK 964

  Fly   637 KVQKVG--YKVEARGFVKVKGKGEMETYWL 664
            .:|:..  ::.|.||...:||||:..||||
Zfish   965 ILQRTDCEFECERRGETFLKGKGKEMTYWL 994

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:462233	30/138 (22%)
		HNOBA	218..479	CDD:462234	53/346 (15%)
		Nucleotidyl_cyc_III	488..665	CDD:448371	79/188 (42%)
gucy2ca	XP_073799927.1	None