DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gyc89Db and gucy2cb

DIOPT Version :10

Sequence 1:NP_650551.1 Gene:Gyc89Db / 42002 FlyBaseID:FBgn0038436 Length:669 Species:Drosophila melanogaster
Sequence 2:XP_696628.5 Gene:gucy2cb / 568219 ZFINID:ZDB-GENE-130531-31 Length:1071 Species:Danio rerio


Alignment Length:565 Identity:151/565 - (26%)
Similarity:241/565 - (42%) Gaps:117/565 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   196 FDNRDY--MAKRVNVIAHPSQLKMPSVDLNVFLELFPFTIVLDHDMKITLAGEKIVE--TWILHN 256
            :.||.|  |.||.:.|:  |||..|       |||..:.::   .:||.   |...|  |:||..
Zfish   447 WQNRYYHHMQKRWSHIS--SQLITP-------LELNEWNMI---SLKIE---EDSTENSTYILRR 496

  Fly   257 PGVNPKTFIGSHILERFKCRRPKDTQ---IQWETILQM---------RTVLFE------FELIRT 303
            ...:.|..    ||:.|:......|:   |:..|:|::         .||.|:      ||....
Zfish   497 ARYDKKIV----ILKEFRLTDGSFTEKQRIELNTLLKIDYCNLTKFYGTVKFDNEYFGVFEYGER 557

  Fly   304 GHNRAAYDAALNFDFENF-----------DEASSLNEAQAMALASAKEFSAENAKEEAAAAATSK 357
            |..|...|..:::..|.|           |.|..::......:|......:.|...:........
Zfish   558 GSLRYVLDDKISYPEETFMDWQFKISVMYDIAKGMSYLHTSNIAVHGRLKSTNCVVDNRMVVKIA 622

  Fly   358 D-----EIDPATGQRRHSVGLR--SILLKGQMFYIKDVDSLIFL---------CSPLIENLDELH 406
            |     .:.|:.........||  .|..||.::....:...|.:         ||...|.|..:.
Zfish   623 DFGFNTIVSPSEDLWTAPEHLRKPGISQKGDVYSFAIISQEIMMRKCTFYTNTCSDRAEKLARVQ 687

  Fly   407 ---GIGLYLNDLNPHGLS------------------------RELVMAGW--------QHCSKLE 436
               ....:..|||....|                        :::.:|.|        :|.|.:|
Zfish   688 YPSTTSFFRPDLNFESTSESEEEVCMLIRNCWDEDPDRRPDFKKIEIALWKIVSRDNQEHESYME 752

  Fly   437 IMFEKEEQRSDELEKSLE----LADSWKRQGDELLYSMIPRPIAERMRKSEEHVCQSFEEVSVIF 497
            .:..:.:..|..||:.:|    |..:.:.:.|.|.:.::|.|:...::::.:...:.|:||::.|
Zfish   753 NLIRRLQMYSRNLERLVEERTALYKAERDRADCLNFMLLPGPVVRSLKETGKVEPELFDEVTIYF 817

  Fly   498 IEVMNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN-PLHA 561
            .:::..  :...:....|:.|..||.::...|..:.:..||||||:|..||.|||.|..| ..||
Zfish   818 SDIVGF--TTLCHFSTPMEVVDMLNDIYKNFDSILDNHDVYKVETIGDAYMVVSGLPRRNGNRHA 880

  Fly   562 EHACDLALRV---MKKVKAHALPGVA--IRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASRMES 621
            :..|.:||.:   |..::...|||:.  ||:|::|||..|||||:|:||||||||||||||||||
Zfish   881 KDICLMALDILAFMGTIQLSHLPGIPVWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMES 945

  Fly   622 SSDPWMIQLSNYTALKVQKVG--YKVEARGFVKVKGKGEMETYWL 664
            :..|..|.:|..|...:|:..  ::.|.||...:||||:..||||
Zfish   946 TGLPLRIHVSQSTINILQRTDCKFEYEERGETFLKGKGKEMTYWL 990

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gyc89DbNP_650551.1 HNOB 2..161 CDD:462233
HNOBA 218..479 CDD:462234 63/346 (18%)
Nucleotidyl_cyc_III 488..665 CDD:448371 78/185 (42%)
gucy2cbXP_696628.5 None
Blue background indicates that the domain is not in the aligned region.

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