Protein Alignment Gyc89Db and npr1b

DIOPT Version :10

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_009290669.2
• Gene: npr1b / 555911
• ZFINID: ZDB-GENE-100805-4
• Length: 1070
• Species: Danio rerio
• Alignment Length: 630
• Identity: 165/630 - (26%)
• Similarity: 266/630 - (42%)
• Gaps: 161/630 - (25%)

  Fly   130 VILYRSGRTGMSKYLIGQMTEVAKEFYGLDMTAYVLESQN-----DICGGTAGPIKLTEGPLTVI 189
            |.:||  :..:.|.|:.|:..::.:...:......|.|..     .:.|...|.:..|:|...|.
Zfish   501 VFIYR--KLKLEKELVAQLWRISWDDIQMSHLEKALRSTGSKLTLSLRGSNYGSLLTTDGNFQVF 563

  Fly   190 VK--------YRLDFDNR---------------------DYMAKRVNVIAHPSQLKM-----PSV 220
            .|        ..:.:.||                     :::.:.:.....|..:.:     |..
Zfish   564 AKTGYFKGNIVAIKYINRRRVELTRKVLFELKHMRDVQNEHLTRFIGACIDPPNICIVTEYCPRG 628

  Fly   221 DLNVFLELFPFTIVLDHDMKITLAGEKIVETWILHNPGVNPKTFIGSH-ILERFKCRRPKDTQIQ 284
            .|...||  ..:|.||...|.:|..:.:.....|||      :.|.|| .|:...|
Zfish   629 SLQNILE--NDSITLDWMFKYSLISDIVKGMAFLHN------SVIVSHGNLKSSNC--------- 676

  Fly   285 WETILQMRTVL----FEFELIRTGHNRAAYDAALNFDFENFDEASSLNEAQAMALASAKEFSAEN 345
               ::..|.||    :....|||                                    |...|:
Zfish   677 ---VVDNRFVLKITDYGLSSIRT------------------------------------ESDTED 702

  Fly   346 AKEEAA-----AAATSKDEIDPATGQRR---HSVG--LRSILLKGQMFYIKDVDSLIFLCSPLIE 400
            |....|     |...|:.|..|..|.::   :|.|  |:.:.|:..:||::.     .|.||. |
Zfish   703 AHSYYARKLWLAPELSRMECFPPGGTQKGDVYSFGIILQEVALRRGVFYLEG-----DLLSPK-E 761

  Fly   401 NLDELH-GIGLYLN-DLNPHGLSRELVMAGWQHC-----------SKLEIMFEKE--EQRSDELE 450
            .:|.:. |...||. .|||...|.||... .|.|           |.:.::..|:  |.||:.|:
Zfish   762 IVDRVALGEWPYLRPSLNPQAHSEELGQL-MQRCWAEEPSDRPEFSHISVLLRKQNREHRSNILD 825

  Fly   451 KSLELADSW------------------KRQGDELLYSMIPRPIAERMRKSEEHVCQSFEEVSVIF 497
            ..|...:.:                  ||:.:.|||.::|..:||::::.|....::|:.|::.|
Zfish   826 NLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYF 890

  Fly   498 IEVMNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN-PLHA 561
            .:::......:.:  ..:|.||.||.:::..|..|.:..||||||:|..||.|||.|..| .||.
Zfish   891 SDIVGFTSLSAES--TPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHG 953

  Fly   562 EHACDLALRVMKKVKAHAL-----PGVAIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASRMES 621
            .....::|.:::.||...:     ..:.:|:||:||||.|||||:|:||||||||||||:|||||
Zfish   954 REIARMSLALLEAVKTFKIRHRPDEQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTSSRMES 1018

  Fly   622 SSDPWMIQLSNYTALKVQKVG-YKVEARGFVKVKGKGEMETYWLL 665
            :.:|..|.:|:.|...:|:.. :::|.||.|::||||:|.|||||
Zfish  1019 NGEPLKIHVSSATRAVLQEFNCFQLELRGDVEMKGKGKMRTYWLL 1063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:462233	6/30 (20%)
		HNOBA	218..479	CDD:462234	69/308 (22%)
		Nucleotidyl_cyc_III	488..665	CDD:448371	76/183 (42%)
npr1b	XP_009290669.2	Periplasmic_Binding_Protein_type1	50..453	CDD:471960
		PK_GC-A_B	544..818	CDD:270944	65/336 (19%)
		HNOBA	<818..872	CDD:462234	13/53 (25%)
		CYCc	851..1036	CDD:214485	72/186 (39%)