Protein Alignment Gyc89Db and Gycalpha99B

DIOPT Version :10

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_477088.2
• Gene: Gycalpha99B / 43493
• FlyBaseID: FBgn0013972
• Length: 676
• Species: Drosophila melanogaster
• Alignment Length: 628
• Identity: 140/628 - (22%)
• Similarity: 259/628 - (41%)
• Gaps: 156/628 - (24%)

  Fly    83 DKMIRSTGRYFCDFLQSIDNIHVQMRFTYPKMKSPSMQLTNMDDDGAV------ILYRSGRTGMS 141
            ::..|..|....:||.|:|.:       |..:|   :|..::.|.|.|      :::.|.|..::
  Fly   131 ERAFRCLGTDLQEFLGSLDGV-------YDVLK---LQEEDVTDTGFVCAGEGELIFTSERPVIA 185

  Fly   142 KYLIGQMTEVAKEFYGLDMTAYVLESQNDICGGTAGPIKLTEGPLTVIVKYRLDF----DNRDYM 202
            ..|:|.:..:.:..|.:|:..               .|:..||...   :||..|    ||...|
  Fly   186 WLLLGSLKALTRMLYKVDVNI---------------KIEPVEGDAR---RYRYLFSLVKDNSQTM 232

  Fly   203 ---------------AKRVNVIAHPSQLKMPSVDLNVFLELFPFTIVLDHDMKITLAGEKIVETW 252
                           .:|.| .::.|.|:|.|   :.|.::||:..:::..:::...|....:
  Fly   233 LMGRPTSVSKTIPETVQRSN-SSNASDLQMNS---SSFCKMFPWHFIMNEQLELVQLGRGFSK-- 291

  Fly   253 ILHNP-----GVNPKTFIGSHILERFKCRRPKDTQIQWETILQMRTVLFEFELIRTGHNRAAYDA 312
             |:.|     |....|:        |..:|||...:::..|::.....|   ||...:...|.|.
  Fly   292 -LYKPYMADFGCQATTY--------FDFKRPKGLTMKFRDIVRRTYTPF---LIGLNNPPGAVDF 344

  Fly   313 ALNFDFENFDEASSLNEAQAMALASAKEFSAENAKEEAAAAATSKDEIDPATGQRRHSVGLRSIL 377
                                                             ||.|          :.
  Fly   345 -------------------------------------------------PAIG----------LE 350

  Fly   378 LKGQMFYIKDVDSLIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKE 442
            :||||.:..:.:||:|:.||.::.||.|...||:::|:..|..:||:::.|.|..::     :..
  Fly   351 IKGQMVHCPESNSLLFIGSPFLDGLDGLTCNGLFISDIPLHDATREVILVGEQARAQ-----DGL 410

  Fly   443 EQRSDELEKSLELADS----WKRQGDELLYSMIPRPIAERMRKSEEHVCQSFEEVSVIFIEVMNI 503
            .:|.|:::.|:|.|:|    .:::...||:.:.|..|||::........:::.:|:::|.:::..
  Fly   411 RRRMDKIKNSIEEANSAVTKERKKNVSLLHLIFPAEIAEKLWLGSSIDAKTYPDVTILFSDIVGF 475

  Fly   504 YDSGSNNIQDAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVNPLHAEHACDLA 568
            ....|.  ......::.|..::...||......||||||:|..|...||....:...|.....:|
  Fly   476 TSICSR--ATPFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGLHRASIYDAHKVAWMA 538

  Fly   569 LRVMKKVKAHAL---PGVAIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASRMESSSDPWMIQL 630
            |:::.....|..   ..:.:|:|:::|.|:|||||.|:|||||||.:|..|::.||.|:...|.:
  Fly   539 LKMIDACSKHITHDGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIANKFESGSEALKINV 603

  Fly   631 SNYTALKVQK-VGYKVEAR----GFV--KVKGKGEMETYWLLE 666
            |..|...:.| .|::.|.:    .|:  :....|..||.:.||
  Fly   604 SPTTKDWLTKHEGFEFELQPRDPSFLPKEFPNPGGTETCYFLE 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:462233	18/83 (22%)
		HNOBA	218..479	CDD:462234	54/269 (20%)
		Nucleotidyl_cyc_III	488..665	CDD:448371	52/186 (28%)
Gycalpha99B	NP_477088.2	HNOB	<109..208	CDD:462233	18/101 (18%)
		HNOBA	259..451	CDD:462234	56/272 (21%)
		Guanylate_cyc	457..647	CDD:425528	54/192 (28%)