Protein Alignment Gyc89Db and Gucy2f

DIOPT Version :10

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001007577.1
• Gene: Gucy2f / 245650
• MGIID: 105119
• Length: 1108
• Species: Mus musculus
• Alignment Length: 285
• Identity: 53/285 - (18%)
• Similarity: 97/285 - (34%)
• Gaps: 96/285 - (33%)

  Fly    24 NNEMNRMKEDME----ILLNTWTVEEIRSIFNGPTRYRCLIEQLQGETLTEKCSSALRVGGFTFL 84
            ||:.::..:..:    :.||. :..|:..:||.|.|                     |.....:.
Mouse   124 NNDTDKSTDTSQKTSRLALNK-SGAELFGLFNYPGR---------------------RSAQLKYY 166

  Fly    85 TDAIHLCDFTMAEHLRLTKMNVFSHLISR--------DNFFRPKSKNVETKHIEQDDVKLFDLLK 141
            |..:.|...|.::.:...:.|...|:...        |.:|:..:.|.:..      ||..|.:.
Mouse   167 TVKVPLRVQTQSDGIWSLEANWLDHMTQHFNNGASLVDGYFQINNHNNDVL------VKTVDSVF 225

  Fly   142 LPPEMIEQIMQRSAYKDA----------------------QSLA-----ITCSAANNIYRQNS-- 177
            :..|.:|.....:|..||                      ||||     :||.....|.:.||
Mouse   226 VFQEGVEGDTNSAAAYDAIVVEQWTIIDGLEVKTDYIPLLQSLASFGWRLTCVLPTPITKTNSDG 290

  Fly   178 ----------LKMVLP-------DVILILDFSSGEMNVRWILEKNQQENESDPDSEKCLNQSEVN 225
                      .:.|||       .||......|.:.:|: ...||:::.:|.|..||     |::
Mouse   291 SLATKQIVFLQRPVLPRKKKESKKVIFKARNKSNKNSVK-DAPKNKKKKDSTPTVEK-----EIS 349

  Fly   226 EKKKTQLLRNTTILKIVTTDDFEPE 250
            ::|..:.:.:|.    .:.::..||
Mouse   350 DQKAERSVEDTN----TSVNERRPE 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:462233	26/170 (15%)
		HNOBA	218..479	CDD:462234	5/33 (15%)
		Nucleotidyl_cyc_III	488..665	CDD:448371
Gucy2f	NP_001007577.1	PBP1_sensory_GC_DEF-like	54..435	CDD:380594	53/285 (19%)
		Protein Kinases, catalytic domain	545..815	CDD:473864
		HNOBA	<824..869	CDD:462234
		CYCc	848..1040	CDD:214485