Protein Alignment Gyc89Db and Npr2

DIOPT Version :10

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_776149.1
• Gene: Npr2 / 230103
• MGIID: 97372
• Length: 1047
• Species: Mus musculus
• Alignment Length: 677
• Identity: 172/677 - (25%)
• Similarity: 285/677 - (42%)
• Gaps: 185/677 - (27%)

  Fly   112 PKMKSPSMQLTNMDDDG---------AVILYRSGRT----GMSKYLIGQMTEVAKEFYGLDMTAY 163
            |.:.:|.... ::||..         |::...:|.|    |:|.:||.:...:.||...:.....
Mouse   432 PPLDNPPCAF-DLDDPSCDKTPLSTLAIVALGTGVTFIMFGVSSFLIFRKLMLEKELASMLWRIR 495

  Fly   164 VLESQ---ND-------------ICGGTAGPIKLTEGPLTVIVKYRLDFDNRDYMAKRVNVIAHP 212
            ..|.|   :|             :.|.:.|.:....|      ||:: |.|..:....|..|.|.
Mouse   496 WEELQFGNSDRYHKGAGSRLTLSLRGSSYGSLMTAHG------KYQI-FANTGHFKGNVVAIKHV 553

  Fly   213 S------------QLK-MPSVDLN----------------VFLELFP----------FTIVLDHD 238
            :            :|| |..|..|                :..|..|          .:|.||..
Mouse   554 NKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWM 618

  Fly   239 MKITLAGEKIVETWILHNPGVNPKTFIGSH-ILERFKCRRPKDTQIQWETILQMRTVLFEFELIR 302
            .:.:|..:.:.....|||      :.|.|| .|:...|            ::..|     |.|..
Mouse   619 FRYSLINDLVKGMAFLHN------SIISSHGSLKSSNC------------VVDSR-----FVLKI 660

  Fly   303 TGHNRAAYDAALNFDFENFDEASSLNEAQAMALASAKEFSAENAKEEAAAAATSKDEIDPATGQR 367
            |.:..|:        |.:..|....:...|..|.:|.|..:.|..              |.||.:
Mouse   661 TDYGLAS--------FRSTAEPDDSHALYAKKLWTAPELLSGNPL--------------PTTGMQ 703

  Fly   368 R-----HSVGLRSILLKGQMFYIKDVDSLIFLCSP--LIENLDELHGIGLYLN-DLNPHGLSREL 424
            :     .::.|:.|.|:...||::.:|     .||  :::.:  .:|...|.. .::...|:.||
Mouse   704 KADVYSFAIILQEIALRSGPFYLEGLD-----LSPKEIVQKV--RNGQRPYFRPSIDRTQLNEEL 761

  Fly   425 VMAGWQHC---------------------------SKLEIMFEKEEQRSDELEKSLE------LA 456
            |:. .:.|                           |.|:.:..:.||.::.|||.:|      |.
Mouse   762 VLL-MERCWAQDPTERPDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLE 825

  Fly   457 DSWKRQGDELLYSMIPRPIAERMRKSEEHVCQSFEEVSVIFIEVMNIYDSGSNNIQDAMQAVTTL 521
            :  ||:.:.|||.::|..:||::::.|....::|:.|::.|.:::......:.:  ..||.||.|
Mouse   826 E--KRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAES--TPMQVVTLL 886

  Fly   522 NKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN-PLHAEHACDLALRVMKKVKAHAL----- 580
            |.:::..|..|.:..||||||:|..||.|||.|..| ..||.....:||.::..|.:..:
Mouse   887 NDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPH 951

  Fly   581 PGVAIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASRMESSSDPWMIQLSNYTALKVQKVG-YK 644
            ..:.:|:|:::|||.|||||:|:||||||||||||||||||:.....|.:|:.|...:.::| ::
Mouse   952 DQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQ 1016

  Fly   645 VEARGFVKVKGKGEMETYWLL---EGP 668
            :|.||.|::||||:|.|||||   :||
Mouse  1017 LELRGDVEMKGKGKMRTYWLLGEQKGP 1043

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:462233	13/61 (21%)
		HNOBA	218..479	CDD:462234	63/328 (19%)
		Nucleotidyl_cyc_III	488..665	CDD:448371	75/183 (41%)
Npr2	NP_776149.1	PBP1_NPR_B	26..421	CDD:380607
		PK_GC-A_B	518..792	CDD:270944	59/333 (18%)
		HNOBA	<798..846	CDD:462234	16/49 (33%)
		CYCc	825..1009	CDD:214485	71/187 (38%)