Protein Alignment Gyc89Db and gcy-34

DIOPT Version :10

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_506319.1
• Gene: gcy-34 / 191656
• WormBaseID: WBGene00001554
• Length: 686
• Species: Caenorhabditis elegans
• Alignment Length: 703
• Identity: 180/703 - (25%)
• Similarity: 319/703 - (45%)
• Gaps: 112/703 - (15%)

  Fly     1 MYGMLYESVQHYIQQEYGMETWRKVCQIVDCKHQSFK------THQIYPDK----LMPDFAAALS 55
            |:|.::||::..:.::||.:.|.:|.:     ...|:      .:..|.|.    |:...:..|.
 Worm     1 MFGFIHESIRQLVIRKYGEDVWLQVLE-----RSGFENGKENIVNHYYSDTDTYVLVDSVSIVLK 60

  Fly    56 ASTGESFDFCMNFFGRCFVRFFSNFGYDKMIRSTGRYFCDFLQSIDNIHVQMRFTYPK--MKSPS 118
            .:..:.::    .:|...:.:....|:|:::||.......||.::|::|..:.....|  ::.||
 Worm    61 VTKDQIWE----MYGGFLITYSMEIGWDELVRSMSPNLKGFLDNLDSLHYFIDHVVYKANLRGPS 121

  Fly   119 MQLTNMDDDGAVILYRSGRTGMSKYLIGQMTEVAKEFYGLDMTAYVLESQNDICGGTAGPIKLTE 183
            .:.....|...::.|.:||.|:...:.|.:.||||..:.||::..|.       |.|...:.:..
 Worm   122 FRCEENPDGTLMLHYFTGRPGLYHIVKGVVKEVAKLVFNLDISLVVQ-------GRTQRSVHMNN 179

  Fly   184 GP-----LTVIVKYRLDFDNRDYMAKRVNVIAH---------PSQLKMPSVDLNVFLELFPFTIV 234
            |.     :..::| .::...||......:.:..         ...||   |.|..|....|:..|
 Worm   180 GERVEEHVIFLIK-NVEEPRRDSDTSTTSALTSVEPDFGEIIDDNLK---VSLQDFSRALPYHFV 240

  Fly   235 LDHDMKITLAGEKIVETWILHNPGVNPKTFIGSHILERFKCRRPKDTQIQWETILQMRTVLFEFE 299
            ||...::...|::      |:|...|.....|:.||..|:..||:
 Worm   241 LDESCRLVQCGDE------LYNHIPNELLQPGTPILRIFEINRPQ-------------------- 279

  Fly   300 LIRTGHNRAAYDAALNFDFENFDEASSLNEAQAMALASA----KEFSAENAKEEAAAAATSKDEI 360
                          :..||||.  .:.:|....:.:.::    |..:|...:|........::|:
 Worm   280 --------------IPLDFENI--CNFINAVFVLQVKTSPLRKKHMNAMTKEEREQEVEAMEEEV 328

  Fly   361 DPATGQRRHSVGLRSILLKGQMFYIKDVDSLIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELV 425
            :  :.:......|:   |||||..:.....:|:||||.:.:::||...|:.|..:..|..:|:|:
 Worm   329 E--SNELTQGCHLK---LKGQMMMLSTKKHIIYLCSPYVTSINELMQFGMRLTAMPLHDATRDLI 388

  Fly   426 MAGWQHCSKLEIMFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERMRKSEEHVCQSF 490
            :...|..|.:|:..:. |..:::||......:..:::.|.:|..|:||.||::: .|.||:....
 Worm   389 LLNQQRLSDVEVNLQL-EANNEQLETMTHELEVERQKTDSILKDMLPRKIAKQL-LSGEHLEPCE 451

  Fly   491 EEVSVIFIEVMNIYDSGSNNIQDAMQ---AVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSG 552
            .|.:|:|.::     .....|....|   .|..||:||..||..::...|||||||...||.|||
 Worm   452 YEATVMFCDL-----PAFQQIIPVCQPKNIVKLLNEVFFKLDRIVVLRGVYKVETVSDSYMTVSG 511

  Fly   553 APDVNPLHAEHACDLALRVMKKVKAHALP----GVAIRVGINSGPVVAGVVGMKVPRYCLFGDTV 613
            .||....|||:.|.:||.:|.:.::...|    ...:|:|::||.::|||||.|:|||||||:||
 Worm   512 IPDYTSEHAENMCHVALGMMWEARSVMDPVNKTPFLLRIGLHSGTIIAGVVGTKMPRYCLFGETV 576

  Fly   614 NTASRMESSSDPWMIQLSNYTALKVQKVG-YKVEARGFVKVKGKGEMETYWLL 665
            ..||:|||......||.|::|..|..:.| ::...||.:.|||:|::|||:|:
 Worm   577 TLASQMESLGVAGKIQCSSWTYSKAMETGRFEFSPRGRINVKGRGDVETYFLM 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:462233	36/170 (21%)
		HNOBA	218..479	CDD:462234	57/264 (22%)
		Nucleotidyl_cyc_III	488..665	CDD:448371	73/184 (40%)
gcy-34	NP_506319.1	HNOB	3..167	CDD:462233	36/172 (21%)
		HNOBA	224..441	CDD:462234	59/267 (22%)
		CYCc	421..609	CDD:214485	74/193 (38%)