Protein Alignment Gyc89Db and gcy-31

DIOPT Version :10

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001024889.1
• Gene: gcy-31 / 191655
• WormBaseID: WBGene00001551
• Length: 702
• Species: Caenorhabditis elegans
• Alignment Length: 703
• Identity: 194/703 - (27%)
• Similarity: 345/703 - (49%)
• Gaps: 121/703 - (17%)

  Fly     1 MYGMLYESVQHYIQQEYGMETWRKVCQIVDCKHQSFKTHQIYPDKLMPDFAAALSASTGESFDFC 65
            |||::.:.:..||:::||..||.:|..:......:|:..:.:.:.|......|....||:..|..
 Worm     1 MYGLIIDHIATYIKEKYGESTWSEVKFVSGVTDDTFQMDKKFSEGLSHKLIWACHDVTGDPVDEL 65

  Fly    66 MNFFGRCFVRFFSNFGYDKMIRSTGRYFCDFLQSIDNIHVQMRFTYPKMKSPSMQLTNMDDDGAV 130
            |...|..|.:|.:.|.::|::|..||.|..||..:||:|..:|||:||:|.||....:....|..
 Worm    66 MTNIGTSFYKFLTKFEFNKVLRVLGRTFPQFLNGLDNLHEYLRFTFPKLKPPSFYCEHESRTGLT 130

  Fly   131 ILYRSGRTGMSKYLIGQMTEVAKEFYGLDMTAYVLESQNDICGGTAGPIKLTEGPLTVIVKYRLD 195
            :.|||.|.|...|:.||:..:::|.:..::...:|:.::|        :.|..      |..||.
 Worm   131 LHYRSKRRGFLHYVQGQIRNISQELFQTEVVIELLDIEHD--------LNLEH------VIMRLH 181

  Fly   196 FDNRDYMAKRV---NVIAHPSQLKMPSVDLNVFLELFPFTIVLDHDMKIT------------LAG 245
            |:|.|:..:..   |:  :.|.|:...:..::|.::|||.||.:..|:|.            :.|
 Worm   182 FNNLDFNRQGTAYRNL--NDSILEKVKITSDIFFDIFPFIIVFNRGMRIRNIGIGLLRVMAGIVG 244

  Fly   246 EKIVETWILHNPGVNPKTFIGSHILERFKCRRPKDTQIQWETILQMRTVLFEFELIRTGHNRAAY 310
            :||.:|::|..|      ||      ||:          ||.|:.....:||.
 Worm   245 KKINQTFLLMRP------FI------RFR----------WEEIMLHSNNIFEL------------ 275

  Fly   311 DAALNFDFENFDEASSLNEAQAMALASAKEFSAENAKEEAAAAATSK-DEIDPATGQRRHSVG-- 372
                                          .|::..:|:.......| .::|..| :.||.:|
 Worm   276 ------------------------------ISSDPIQEDEDGILVYKTTDVDQMT-EERHRMGDG 309

  Fly   373 --LRSILLKGQMFYIKDVDSLIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKL 435
              .:.:.|||||||:::.:|:.|:..|::.:|.:::..||::||...|..||:||:|..|..::|
 Worm   310 EREKFLSLKGQMFYMEEWESICFVGIPVMSHLPQMYKSGLFINDFALHDSSRDLVLASTQQSAEL 374

  Fly   436 EIMFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERMRKSEEHV--CQSFEEVSVIFI 498
            :::..:|.|:|..:.:::......:|:.|:|||.|:|:.:|.::|..|..|  |:.|:.|:::|.
 Worm   375 KLLLHQEAQKSRNMRENMNRLKKERRRTDKLLYQMLPKSVANQLRHGESAVACCERFDSVTILFT 439

  Fly   499 EVMNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVNPLHAEH 563
            :::......|:  ...::.:..|..:::..|:.|.:..||||||:|..||.|||||......||.
 Worm   440 DIVEFTKMCSS--LTPLEVIEFLKVIYTNFDKIIDTHGVYKVETIGDAYMVVSGAPTKTEHDAEF 502

  Fly   564 ACDLALRVMKKV--------KAHALPGVAIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASRME 620
            ..|.|.:.:.:.        |.|.   :.||.|::||.|||||||:.:|||||||:||..|::||
 Worm   503 ILDCASQFLVEAGKMVNMNNKIHK---IDIRAGVHSGSVVAGVVGLSMPRYCLFGETVYVANKME 564

  Fly   621 SSSDPWMIQLSNYTALKVQKVG---YKVEARGFVKVKGKGEMETYWLL--EGP 668
            .:|.|..|.:|..|..|:::..   |:.|.|..:::|....::|::::  .||
 Worm   565 QNSSPMKILVSETTHNKIEESDPGLYQFERREEIEIKDDQTIQTFFVVSRHGP 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:462233	48/158 (30%)
		HNOBA	218..479	CDD:462234	65/277 (23%)
		Nucleotidyl_cyc_III	488..665	CDD:448371	62/187 (33%)
gcy-31	NP_001024889.1	HNOB	2..163	CDD:462233	48/160 (30%)
		HNOBA	221..418	CDD:462234	60/261 (23%)
		CYCc	397..592	CDD:214485	70/199 (35%)