Protein Alignment Gyc89Db and Npr1

DIOPT Version :10

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_032753.5
• Gene: Npr1 / 18160
• MGIID: 97371
• Length: 1057
• Species: Mus musculus
• Alignment Length: 593
• Identity: 164/593 - (27%)
• Similarity: 263/593 - (44%)
• Gaps: 136/593 - (22%)

  Fly   135 SGRTGMSKYLIGQMTEVAKEFYGLDMTAYVLESQNDICGGTAGPIKLTEGPLTVIVKYRLDFDNR 199
            |||.  |.|  |.:.....:|.....|||...:...:.......|:||...|..: |:..|..|
Mouse   530 SGRG--SNY--GSLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFEL-KHMRDVQN- 588

  Fly   200 DYMAKRVNVIAHPSQLKM-----PSVDLNVFLELFPFTIVLDHDMKITLAGEKIVETWILHNPGV 259
            :::.:.|.....|..:.:     |...|...||  ..:|.||...:.:|..:.:.....|||..
Mouse   589 EHLTRFVGACTDPPNICILTEYCPRGSLQDILE--NESITLDWMFRYSLTNDIVKGMLFLHNGA- 650

  Fly   260 NPKTFIGSH-ILERFKCRRPKDTQIQWETILQMRTVLFEFELIRTGHNRAAYDAALNFDFENFDE 323
                 |||| .|:...|            ::..|.||                ...::..|:|.:
Mouse   651 -----IGSHGNLKSSNC------------VVDGRFVL----------------KITDYGLESFRD 682

  Fly   324 ASSLNEAQAMALASAKEFSAENAKEEAAAAATSKDEIDPATGQRR---HSVG--LRSILLKGQMF 383
            .   ...|...|.:.|.::|......|:         .||.|.:.   :|.|  |:.|.|:..:|
Mouse   683 P---EPEQGHTLFAKKLWTAPELLRMAS---------PPARGSQAGDVYSFGIILQEIALRSGVF 735

  Fly   384 YIKDVDSLIFLCSP--LIE------------------NLDEL------------------HGIGL 410
            |::.:|     .||  :||                  :|:||                  ..|.|
Mouse   736 YVEGLD-----LSPKEIIERVTRGEQPPFRPSMDLQSHLEELGQLMQRCWAEDPQERPPFQQIRL 795

  Fly   411 YLNDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRSDELEKSLE------LADSWKRQGDELLYS 469
            .|...|....|           :.|:.:..:.||.::.||:.:|      |.:  ||:.:.|||.
Mouse   796 ALRKFNKENSS-----------NILDNLLSRMEQYANNLEELVEERTQAYLEE--KRKAEALLYQ 847

  Fly   470 MIPRPIAERMRKSEEHVCQSFEEVSVIFIEVMNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIIS 534
            ::|..:||::::.|....::|:.|::.|.:::......:.:  ..||.||.||.:::..|..|.:
Mouse   848 ILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAES--TPMQVVTLLNDLYTCFDAVIDN 910

  Fly   535 PFVYKVETVGMVYMAVSGAPDVN-PLHAEHACDLALRVMKKVKAHAL-----PGVAIRVGINSGP 593
            ..||||||:|..||.|||.|..| .|||.....:||.::..|::..:     ..:.:|:||::||
Mouse   911 FDVYKVETIGDAYMVVSGLPVRNGQLHAREVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGP 975

  Fly   594 VVAGVVGMKVPRYCLFGDTVNTASRMESSSDPWMIQLSNYTALKVQKV-GYKVEARGFVKVKGKG 657
            |.|||||:|:||||||||||||||||||:.:...|.||:.|...:::. |:::|.||.|::||||
Mouse   976 VCAGVVGLKMPRYCLFGDTVNTASRMESNGEALRIHLSSETKAVLEEFDGFELELRGDVEMKGKG 1040

  Fly   658 EMETYWLL 665
            ::.|||||
Mouse  1041 KVRTYWLL 1048

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:462233	7/25 (28%)
		HNOBA	218..479	CDD:462234	65/310 (21%)
		Nucleotidyl_cyc_III	488..665	CDD:448371	77/183 (42%)
Npr1	NP_032753.5	PBP1_NPR_A	32..439	CDD:380608
		PK_GC-A_B	530..803	CDD:270944	68/331 (21%)
		HNOBA	<809..857	CDD:462234	15/49 (31%)
		CYCc	836..1025	CDD:214485	74/192 (39%)