Protein Alignment Gyc89Db and gcy-32

DIOPT Version :10

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_506452.5
• Gene: gcy-32 / 179887
• WormBaseID: WBGene00001552
• Length: 684
• Species: Caenorhabditis elegans
• Alignment Length: 704
• Identity: 185/704 - (26%)
• Similarity: 313/704 - (44%)
• Gaps: 117/704 - (16%)

  Fly     1 MYGMLYESVQHYIQQEYGMETWRKVCQIVDCKHQSFKT------HQIYPDK----LMPDFAAALS 55
            |:|.::||::..:.:.||.:||.:|.:     ...|::      :..|.|.    |:...:..|.
 Worm     1 MFGFIHESIRQLVIRNYGEDTWTQVLE-----RSGFESGKENIMNHYYSDTDTYVLVDSVSLVLK 60

  Fly    56 ASTGESFDFCMNFFGRCFVRFFSNFGYDKMIRSTGRYFCDFLQSIDNIHVQMRFTYPK--MKSPS 118
            .:..:.::    .:|...:.:....|:|:::||.......||.::|::|..:.....|  ::.||
 Worm    61 VTKDQVWE----MYGGFLITYSMEIGWDELVRSMSPNLKGFLDNLDSLHYFIDHVVYKANLRGPS 121

  Fly   119 MQLTNMDDDGAVILYRSGRTGMSKYLIGQMTEVAKEFYGLDMTAYVLESQNDICGGTAGPIKLTE 183
            .:.....|...::.|.:||.|:...:.|.:.||||..:.||:|..|.       |.|...:.:..
 Worm   122 FRCEETPDGTLLLHYFTGRPGLYHIVKGVVKEVAKRVFDLDITLVVQ-------GRTQRSVHMNN 179

  Fly   184 GPL----TVIVKYRLDFDNRDYMAKRVNVIAHPSQLKMPS-------VDLNVFLELFPFTIVLDH 237
            |..    .|.:...|....||.....|:::. .:....|:       :.|:.|.:..|:..|:|.
 Worm   180 GERVEEHVVFLINNLSEPRRDSEGSEVSLLT-STNANFPTIVDDTLGISLDDFSKALPYHFVIDE 243

  Fly   238 DMKITLAGEKIVETWILHNPGVNPKTFIGSHILERFKCRRPKDTQIQWETILQMRTVLFEFEL-- 300
            ..|:...|.:      |||...|.....|:.||..|:..||: ..:.:|.|......:|..::
 Worm   244 SCKLVQCGSE------LHNHIPNELLQPGTPILRIFEINRPQ-IPLDFENICNFINAVFVLQVKT 301

  Fly   301 --IRTGHNRAAYDAALNFDFENFDEASSLNEAQAMALASAKEFSAENAKEEAAAAATSKDEIDPA 363
              ::..|..|.....|..:.|..|| .:.||..
 Worm   302 SPLKKKHMDAMSQEELKQEMETLDE-DATNELT-------------------------------- 333

  Fly   364 TGQRRHSVGLRSILLKGQMFYIKDVDSLIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELVMAG 428
              |..|      :.|||||..:.....:|:||||.:.:::||...|:.|..:..|..:|:|::..
 Worm   334 --QGHH------LKLKGQMMLLASKKHIIYLCSPYVTSINELMQYGMRLTAMPLHDATRDLILLN 390

  Fly   429 WQHCSKLEI--MFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERMRKSEEHVCQSFE 491
            .|..|.:|:  ..|...::.:.:.:.|||.   :::.|.:|..|:||.||::: .|.||:.....
 Worm   391 QQRLSDVEVNLQLEANNEQLETMTRELELE---RQKTDSILKDMLPRRIAQQL-LSGEHIEACEH 451

  Fly   492 EVSVIFIEVMNIYDSGSNNIQDAM------QAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAV 550
            |.:|:|.::        ...|.|:      ..|..||::|..||..::...|||||||...||||
 Worm   452 EATVMFCDL--------PAFQQAIPQCSPKDIVNMLNEIFRKLDRIVVIRGVYKVETVSDSYMAV 508

  Fly   551 SGAPDVNPLHAEHACDLALRVMKKVKAHALP----GVAIRVGINSGPVVAGVVGMKVPRYCLFGD 611
            ||.||..|.|||:.|.:||.:|.:.::...|    ...:|:||:||.:.|||||...|:|||||:
 Worm   509 SGIPDYTPEHAENMCHVALGMMWEARSVIDPVSKTPFLLRIGIHSGTITAGVVGTVHPKYCLFGE 573

  Fly   612 TVNTASRMESSSDPWMIQLSNYTALKVQKVG-YKVEARGFVKVKGKGEMETYWL 664
            ||..||:|||......||.|.:...|..:.| ::...||.:.||.:|..|||:|
 Worm   574 TVTLASQMESLGMAGKIQCSKWAYQKAMETGRFEFSPRGRIDVKQRGLTETYFL 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:462233	37/170 (22%)
		HNOBA	218..479	CDD:462234	62/273 (23%)
		Nucleotidyl_cyc_III	488..665	CDD:448371	72/188 (38%)
gcy-32	NP_506452.5	HNOB	3..167	CDD:462233	38/172 (22%)
		HNOBA	226..440	CDD:462234	61/264 (23%)
		CYCc	419..608	CDD:214485	74/200 (37%)