Protein Alignment Gyc89Db and gcy-7

DIOPT Version :10

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001360539.1
• Gene: gcy-7 / 179222
• WormBaseID: WBGene00001534
• Length: 1117
• Species: Caenorhabditis elegans
• Alignment Length: 724
• Identity: 170/724 - (23%)
• Similarity: 276/724 - (38%)
• Gaps: 225/724 - (31%)

  Fly     5 LYESVQHYIQQEYGMETWRKVCQI-------VDCKHQSFKTHQIYPDKLMPDFAAALSASTGESF 62
            :|.|:|...|:   :|...::.||       ::.|.:....|.:   :.:....:.||:.|..||
 Worm   509 IYFSIQARRQE---IERLNRLWQIPFIHLHQINSKQKGKGEHSV---RSLQSGTSTLSSRTTVSF 567

  Fly    63 DF-CMNFFGRCFVRFFS---NFGYDKMIRSTGRY-------FCDFLQSIDNIHVQMRFTYPKMKS 116
            .. ..||.      |||   ...|:.::.....|       .|.|::|
 Worm   568 KTESRNFL------FFSLQRESDYEPVVAKKHAYRPRLDDDKCTFMRS----------------- 609

  Fly   117 PSMQLTNMDDDGAVILYRSGRTGMSKYLIGQMTEVAKEFYGLDMTAYVLESQNDICGGTAGPIKL 181
                |.|:|.|.                       ...|.||.:....:.|....|  :.|.|
 Worm   610 ----LRNLDQDN-----------------------LNRFIGLCLDGPQMLSVWRFC--SRGSI-- 643

  Fly   182 TEGPLTVIVKYRLDFDNRDYMAKRVNVIAHPSQLKMPSVDLNVFLELFPFTIVLD--HDMKITLA 244
                ..||:|..:..||                             .|.::::.|  |.:.
 Worm   644 ----ADVILKATIQMDN-----------------------------FFIYSLIKDMVHGLV---- 671

  Fly   245 GEKIVETWILHNPGVNPKTFIGSHILERFKCRRPKDTQIQWET--------------ILQMRTVL 295
                    .||.      :.:|.|.:...||....|   :|:.              :.:.:.:|
 Worm   672 --------FLHG------SMVGYHGMLTSKCCLIDD---RWQVKISNYGLQDLRSPEMYEKKDLL 719

  Fly   296 FEF-ELIRTGHNRAAYDAALNFDFENFDEASSLNEAQAMALASAKEFSAENAKEEAAAAATSKDE 359
            :.. ||:|....:.:.:.          :..||....|..:.....|:.|:.||:       .:|
 Worm   720 WSAPELLRAEDIKGSKEG----------DVYSLGIICAELITRKGVFNMEDRKED-------PEE 767

  Fly   360 I----------DPATG-QRRHSVGLRSILLKGQMFYIKDVDSLIFLC-------SPLIENL-DEL 405
            |          .|... :..|::.:...||    ..::|       |       .|.||.: .:|
 Worm   768 IIYLLKKGGLKSPRPDLEYDHTIEINPALL----HLVRD-------CFTERPSERPSIETVRSQL 821

  Fly   406 HGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRSDELEKSLELADSWKRQGDELLYSM 470
            .|:....||    .|...:......:.|.||   |:..:|:.||.:.       |::.|.|||.|
 Worm   822 RGMNSSRND----NLMDHVFNMLESYASSLE---EEVSERTKELVEE-------KKKSDVLLYRM 872

  Fly   471 IPRPIAERMRKSEEHVCQSFEEVSVIFIEVMNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISP 535
            :|:.:|::::..:....::||:|::.|.:|:......|.  ...:|.|..||.:::..|..|...
 Worm   873 LPKTVADKLKLGQTVEPETFEQVTIFFSDVVQFTTLASK--CTPLQVVNLLNDLYTIFDGIIEKH 935

  Fly   536 FVYKVETVGMVYMAVSGAPDVNPLHAEHACDLALRVMKKVKA-------HALPG--VAIRVGINS 591
            .||||||:|..|:.|||.|..|  ..||...:||..:..:.:       | ||.  :.:|:|:|.
 Worm   936 DVYKVETIGDGYLCVSGLPHRN--GNEHVRQIALMSLAFLSSLQFFRVPH-LPSERINLRIGMNC 997

  Fly   592 GPVVAGVVGMKVPRYCLFGDTVNTASRMESSSDPWMIQLSNYTALKVQKV-GYKVEARGFVKVKG 655
            |.|||||||:.:||:|||||.|||||||||:..|..|.:|......:..| |:..|:||.|.:||
 Worm   998 GSVVAGVVGLTMPRFCLFGDAVNTASRMESNGKPGKIHVSAEANRMLHLVGGFDTESRGEVIIKG 1062

  Fly   656 KGEMETYWL 664
            ||.|||:||
 Worm  1063 KGVMETFWL 1071

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:462233	31/173 (18%)
		HNOBA	218..479	CDD:462234	53/296 (18%)
		Nucleotidyl_cyc_III	488..665	CDD:448371	77/187 (41%)
gcy-7	NP_001360539.1	PBP1_NPR_GC-like	36..438	CDD:380575
		Protein Kinases, catalytic domain	550..822	CDD:473864	64/407 (16%)
		HNOBA	<837..881	CDD:462234	15/53 (28%)
		CYCc	860..1049	CDD:214485	71/200 (36%)