DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gyc89Db and gcy-29

DIOPT Version :10

Sequence 1:NP_650551.1 Gene:Gyc89Db / 42002 FlyBaseID:FBgn0038436 Length:669 Species:Drosophila melanogaster
Sequence 2:NP_001364597.1 Gene:gcy-29 / 175116 WormBaseID:WBGene00007314 Length:1069 Species:Caenorhabditis elegans


Alignment Length:245 Identity:74/245 - (30%)
Similarity:127/245 - (51%) Gaps:20/245 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   435 LEIMFEKEEQRSDELEKSL----ELADSWKRQGDELLYSMIPRPIAERMRKSEEHVCQSFEEVSV 495
            ::.|....|:.::.|||.:    :||:....:.:.||:.::|:.:|..::.......:.::..:|
 Worm   813 VDSMMRMMEEYANNLEKLVGERTKLAEEANLRAERLLFQLLPKHVAIELKAGRTVAPKMYDSATV 877

  Fly   496 IFIEVMNIYDSGSNNIQDA---MQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN 557
            :|.:::     |...:..|   ::.|..|||::|..|..|.....|||||:|..||.|||.|..|
 Worm   878 MFSDIV-----GFTKLCSASTPIEVVNLLNKLYSEFDTVISKHDCYKVETIGDAYMVVSGIPIEN 937

  Fly   558 -PLHAEHACDLALRVMKKVKAHALP-----GVAIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTA 616
             ..|..:...:.|.:|..:|...:|     .:.||:|..||.|.|.|||:..|||||||:|||.|
 Worm   938 GQRHVANISAVTLGIMDLLKVFEVPHRRDYRLTIRLGFASGQVSAAVVGLSSPRYCLFGETVNIA 1002

  Fly   617 SRMESSSDPWMIQLSNYTALKVQK--VGYKVEARGFVKVKGKGEMETYWL 664
            :.||||.:...:|::..:.:.::.  ..:.:|.||..|...:.:..||||
 Worm  1003 AVMESSGEGGRVQITETSKILLENEYPEFIIEIRGINKDVKQDDFVTYWL 1052

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gyc89DbNP_650551.1 HNOB 2..161 CDD:462233
HNOBA 218..479 CDD:462234 11/47 (23%)
Nucleotidyl_cyc_III 488..665 CDD:448371 63/188 (34%)
gcy-29NP_001364597.1 PBP1_NPR_GC-like 27..403 CDD:380575
Protein Kinases, catalytic domain 534..804 CDD:473864
CYCc 840..1033 CDD:214485 59/197 (30%)
Blue background indicates that the domain is not in the aligned region.

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