Protein Alignment Gyc89Db and LOC1274705

DIOPT Version :10

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_313866.5
• Gene: LOC1274705 / 1274705
• VectorBaseID: AGAMI1_000741
• Length: 649
• Species: Anopheles gambiae
• Alignment Length: 670
• Identity: 385/670 - (57%)
• Similarity: 493/670 - (73%)
• Gaps: 28/670 - (4%)

  Fly     1 MYGMLYESVQHYIQQEYGMETWRKVCQIVDCKHQSFKTHQIYPDKLMPDFAAALSASTGESFDFC 65
            |||||.|||||::|.|||...||:......||:..|.|||:|||.|:||.||||||.||:.||..
Mosquito     1 MYGMLLESVQHFVQLEYGEFVWRQALLTTGCKNTVFNTHQLYPDNLIPDLAAALSAITGKPFDEF 65

  Fly    66 MNFFGRCFVRFFSNFGYDKMIRSTGRYFCDFLQSIDNIHVQMRFTYPKMKSPSMQLTNMDDDGAV 130
            |.||||||||||||||||::|::|||||||||.|:||||:||||||.||||||||||.:|::|||
Mosquito    66 MIFFGRCFVRFFSNFGYDELIKATGRYFCDFLHSVDNIHLQMRFTYRKMKSPSMQLTEVDENGAV 130

  Fly   131 ILYRSGRTGMSKYLIGQMTEVAKEFYGLDMTAYVLESQNDICGGTAGPIKLTEGPLTVIVKYRLD 195
            ::|||.|||.||||.||:.|:||:.||:|::..|||||||..|||:|||....|..|||||||||
Mosquito   131 LVYRSTRTGFSKYLRGQLLEIAKQLYGMDVSIKVLESQNDTPGGTSGPIAPQGGLKTVIVKYRLD 195

  Fly   196 FDNRDYMAKRVNVIAHPSQLKMPSVDLNVFLELFPFTIVLDHDMKITLAGEKIVETWILHNPGVN 260
            ||||:||.:||::.||||||::..|:..:.|.||||.::|:.:||||..|||::|:|:|:|...:
Mosquito   196 FDNREYMQRRVHIKAHPSQLQLTPVNSKLLLNLFPFALILNEEMKITAVGEKLIESWMLNNVNRS 260

  Fly   261 PKTFIGSHILERFKCRRPKDTQIQWETILQMRTVLFEFELIRTGHNRAAYDAALNFDFENFDEAS 325
            |...:|:.:.:.||.|||......||.|.:::|||||.:|::....:...|     :.:..|..:
Mosquito   261 PTELLGAKVTDHFKLRRPSGITFTWENIKRLQTVLFEIQLLKGSSAKGTKD-----ESKIVDTKT 320

  Fly   326 SLNEAQAMALASAKEFSAENAKEEAAAAATSKDEIDPATGQRRHSVGLRSILLKGQMFYIKDVDS 390
            ||::.           ...::.|:||...||.        .||.|.|||||||||:|.||||::|
Mosquito   321 SLSQV-----------DTSSSTEDAAKIMTSI--------PRRGSQGLRSILLKGEMRYIKDINS 366

  Fly   391 LIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRSDELEKSLEL 455
            |:|||||||.||:||..:|||||||||||||||:|.:|:.|.|:|::|.|:||||::|||.||.|
Mosquito   367 LVFLCSPLINNLEELREMGLYLNDLNPHGLSREMVFSGFSHYSRLDLMCEREEQRAEELETSLAL 431

  Fly   456 ADSWKRQGDELLYSMIPRPIAERMRKSE--EHVCQSFEEVSVIFIEVMNIYDSGSNNIQDAMQAV 518
            ||||||||||||||||||.||||:|:.:  ...|||||||:|:|.||.... :|.::|:.||..|
Mosquito   432 ADSWKRQGDELLYSMIPRSIAERLREGQNPHETCQSFEEVTVLFAEVQETI-TGDDSIKYAMTTV 495

  Fly   519 TTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVNPLHAEHACDLALRVMKKVKAHALPGV 583
            .|||..|||.||.|.||..|||||||.||||||||||:||.||:|..||||.::..::...||||
Mosquito   496 NTLNAAFSAFDELIHSPMAYKVETVGKVYMAVSGAPDINPFHAQHMADLALDMLHSIRQLNLPGV 560

  Fly   584 AIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASRMESSSDPWMIQLSNYTALKVQKVGYKVEAR 648
            .:::|.:|||:|||:||:|||||||||||||||||||||.:...||:|.|||.|::|:||.:..|
Mosquito   561 GVKIGFHSGPIVAGIVGLKVPRYCLFGDTVNTASRMESSGETDCIQVSGYTAQKLKKLGYVLAYR 625

  Fly   649 GFVKVKGKGEMETYWLLEGP 668
            |.|.|||||:|||:| |:||
Mosquito   626 GKVAVKGKGDMETFW-LQGP 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:462233	107/158 (68%)
		HNOBA	218..479	CDD:462234	126/260 (48%)
		Nucleotidyl_cyc_III	488..665	CDD:448371	108/176 (61%)
LOC1274705	XP_313866.5	HNOB	2..164	CDD:462233	107/161 (66%)
		HNOBA	219..455	CDD:462234	126/259 (49%)
		Guanylate_cyc	466..643	CDD:425528	109/178 (61%)