DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gyc89Db and Adcy8

DIOPT Version :10

Sequence 1:NP_650551.1 Gene:Gyc89Db / 42002 FlyBaseID:FBgn0038436 Length:669 Species:Drosophila melanogaster
Sequence 2:XP_061499353.1 Gene:Adcy8 / 1269297 VectorBaseID:AGAMI1_003825 Length:1504 Species:Anopheles gambiae


Alignment Length:452 Identity:114/452 - (25%)
Similarity:185/452 - (40%) Gaps:119/452 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   234 VLDHDMKITLAGEKIVETWILHNPGVNPKTFIGSHILERFKCRRPKDTQIQWETILQMRTVLFEF 298
            :||||       |......|||...|:|:..:.:.:|    |            ::.:.|.|..:
Mosquito  1007 LLDHD-------ETTSTPPILHPSCVHPEYVVFTWVL----C------------LISLATALKLY 1048

  Fly   299 ELIRTG---HNRAAYDAALNFDFENFDEASSLNEAQAMALASAKEFSAENAKEEAAAAATSKDEI 360
            .|::|.   ...|.|...:...||...::..|...||..:.                        
Mosquito  1049 YLVKTFMAIAMVACYSFLILLVFEKVFDSYDLQYIQASGMP------------------------ 1089

  Fly   361 DPATGQRRHSVGLRSILLKGQMFYIKDVDSLIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELV 425
                             |..||..:                      :|::|..:..|....|:.
Mosquito  1090 -----------------LAAQMMIL----------------------LGVFLTMVTYHARLVEVT 1115

  Fly   426 MAGWQHCSKLEIMFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAE---RMRKSEEHVC 487
                   |:|:.:::      ::.||.|....|.:...|.|:.:::|..:|.   ...:::|...
Mosquito  1116 -------SRLDFIWK------EQAEKELSNMRSNRHLNDLLIKNILPDHVATYYLSEERTDELYA 1167

  Fly   488 QSFEEVSVIFIEVMNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISP---FVYKVETVGMVYMA 549
            :..|...|:|..:.|..|..|.:|::....:..||::.|..|..:..|   .|.|::|||..|||
Mosquito  1168 KMHELCGVMFASIPNFKDFYSEDIENGKACIRILNEIISDFDSLLEEPRFETVEKIKTVGATYMA 1232

  Fly   550 VSGAPDVNPLHA-----EHACD-----LALR-VMKKVKAHALPGVAIRVGINSGPVVAGVVGMKV 603
            .|........|.     |..||     ||:| .:::|...|.....:||||:|||:|:||:|.:.
Mosquito  1233 ASNLCSTKKSHVDERDEEAVCDLVEFALAMRQKLQEVNKDAFNTFQLRVGISSGPLVSGVIGARK 1297

  Fly   604 PRYCLFGDTVNTASRMESSSDPWMIQLSNYTALKVQKVGYKVEARGFVKVKGKGEMETYWLL 665
            |.|.::|:|||.||||:|:.:.|.:|:.:|||..:|..||....||.|.|||||.|.|||:|
Mosquito  1298 PVYDIWGNTVNVASRMDSTGENWKVQVPDYTAALLQTKGYTCVQRGEVNVKGKGLMLTYWVL 1359

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gyc89DbNP_650551.1 HNOB 2..161 CDD:462233
HNOBA 218..479 CDD:462234 40/250 (16%)
Nucleotidyl_cyc_III 488..665 CDD:448371 72/190 (38%)
Adcy8XP_061499353.1 None
Blue background indicates that the domain is not in the aligned region.

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