Protein Alignment CG10405 and F10

DIOPT Version :10

• Sequence 1: NP_001036717.1
• Gene: CG10405 / 41996
• FlyBaseID: FBgn0038431
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 87/263 - (33%)
• Similarity: 128/263 - (48%)
• Gaps: 36/263 - (13%)

  Fly    19 ILEASRTEAAVPRQPD---SRIVNGREATEGQFPYQ-LSLRRQTVHICGASILSSNWAITAAHCI 79
            :|:.::|:   |.:.|   :|||.|:|..:|:.|:| |.:..:....||.:|||..:.:|||||:
Human   217 LLDFNQTQ---PERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCL 278

  Fly    80 DGHEQQPREFTLRQG---SIMRTSGGTVQPVKAIYKHPAYDRADMNFDVALLRTADGALSLPLG- 140
                .|.:.|.:|.|   :.....|..|..|:.:.||..:.:...:||:|:||     |..|:.
Human   279 ----YQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLR-----LKTPITF 334

  Fly   141 --KVAPIRLPTVGEAISESM---PAVVSGWGHMSTSNPVLSSVLKSTTVLTVNQEKCHNDLRHHG 200
              .|||..||....|.|..|   ..:|||:|....... .|:.||...|..|::..|  .|....
Human   335 RMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGR-QSTRLKMLEVPYVDRNSC--KLSSSF 396

  Fly   201 GVTEAMFCAA--ARNTDACQGDSGGP----ISAQGTLIGIVSWGVGCADPYYPGVYTRLAHPTIR 259
            .:|:.||||.  .:..||||||||||    ......:.||||||.|||.....|:||::.  ...
Human   397 IITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVT--AFL 459

  Fly   260 RWI 262
            :||
Human   460 KWI 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	81/241 (34%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	82/242 (34%)
		O-glycosylated at one site	476..485