DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10405 and klkb1

DIOPT Version :9

Sequence 1:	NP_001036717.1	Gene:	CG10405 / 41996	FlyBaseID:	FBgn0038431	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_002934450.3	Gene:	klkb1 / 100486524	XenbaseID:	XB-GENE-985051	Length:	629	Species:	Xenopus tropicalis

Alignment Length:	254	Identity:	81/254 - (31%)
Similarity:	122/254 - (48%)	Gaps:	35/254 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PRQPDSRIVNGREATEGQFPYQLSLR-RQTV----HICGASILSSNWAITAAHCIDGHEQQPREF 89
            |.:..:|||.|.::..|::|:|:|:. |.|.    |.||.||:|:.|.:|||||...| ..|:.:
Frog   384 PIEHANRIVGGTDSVLGEWPWQVSMHLRLTASYKKHACGGSIISNQWIVTAAHCFAMH-PLPQMW 447

  Fly    90 TLRQGSIMR---TSGGTVQPVKAIYKHPAYDRADMNFDVALLRTADGALSLPL-------GKVAP 144
            .:..|.:..   |........:.|..||.|..|....|:|||:     |..|:       ....|
Frog   448 IIYSGVVKLSNITQSTPFSETEQIIIHPHYTGAGNGTDIALLK-----LKTPISFNDHQKAICLP 507

  Fly   145 IRLPTVGEAISESMPAVVSGWGHMSTSNPVLSSVLKSTTVLTVNQEKCHNDLRHHGGVTEAMFCA 209
            .|.||.  .:..|  ..::|||....|.. |:::|:...|..::.|:|..:. ....:.:.:.||
Frog   508 PREPTF--VLPNS--CWITGWGFTEESGS-LANILQKAEVPQISTEECQGNY-EQTRIDKKILCA 566

  Fly   210 AAR--NTDACQGDSGGPISAQ----GTLIGIVSWGVGCADPYYPGVYTRLAHPTIRRWI 262
            ..:  ..|:|:||||||::..    ..|.||.|||.|||.|..||||||::..|  .||
Frog   567 GYKRGKIDSCKGDSGGPLACVVDEIWYLTGITSWGEGCARPGKPGVYTRVSEFT--DWI 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	78/246 (32%)
CG10405	NP_001036717.1	Tryp_SPc	37..263	CDD:238113	79/247 (32%)
klkb1	XP_002934450.3	APPLE	21..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	290..373	CDD:128519
		Tryp_SPc	391..626	CDD:238113	79/247 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910