Protein Alignment CG6126 and slc22a3

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001107932.1
• Gene: slc22a3 / 797890
• ZFINID: ZDB-GENE-080204-92
• Length: 554
• Species: Danio rerio
• Alignment Length: 572
• Identity: 150/572 - (26%)
• Similarity: 260/572 - (45%)
• Gaps: 53/572 - (9%)

  Fly     8 EDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSSA 72
            ::|:...|:||.||.....|..|..|.....::.:|.:...|:|.|     ..:||......|..
Zfish     5 DELLQHAGDFGFYQKRISVLGSLPILLLAFVLIGVVFLGYTPDHWC-----KTASLQEKCGFSEE 64

  Fly    73 ILAAIPLK---PNGELESCLMFDPSSPGTNTTINCERYVYDTTYYKTSRTIDWNF---------- 124
            .:..:.:.   ..|....|:.|| .:....:.::|...:::.:.:.::....|.|
Zfish    65 QVRDLTVPRTGARGAFSKCVKFD-DALRNGSALSCNISIFNNSTHLSACNEGWTFNENRTTIVTE 128

  Fly   125 ---VCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVA-----FIP 181
               ||:..|:..:.|.....|.|.||:..|.|||:.|||:.|..|     |.|:||:     |.|
Zfish   129 FSLVCEDSWLADLNQVSLAGGFFIGALVTGYLADRFGRKSCFIAS-----IFGLGVSGTCIIFSP 188

  Fly   182 EYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIPDR 246
            .|...:..|.|.|.. :.||:...:||.:|..|...|....:..:..::.|::|:......||..
Zfish   189 YYPLLLFFRCLQGFF-AKGAWTATYVLIIEFFGSNNRKFVSVMSRTFYSLGLVLLPALAYYIPSW 252

  Fly   247 QWLQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVD---KEYYVQK 308
            :.||:...|...:||.:.|.:.||||||..|.:..||:.||....:.|...:|.|   .:..::|
Zfish   253 RNLQLAMTLPTFIFLIYHWVIPESPRWLLSQRKTKEALSIVKSIAKCNKRSLPEDFHEMDLLIEK 317

  Fly   309 AKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGL 373
                  .||.......|||:||.:|..|..:...||..::|:.||.|..|....|.:|...|..:
Zfish   318 ------QEEIMRPSYKDLFKTPKMRKHTFILIYAWFTGAVVFQGLVLRLGITGDNVFLDFLISAV 376

  Fly   374 VEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQG-STTSTAVVMAGKLLIAGSFAVI 437
            ||.|:.:...|::||:|||.:.:|:...||..|:...:|:.. |.....:.:.|:|.:|.....:
Zfish   377 VELPTGLIFYFLVDRIGRRPLMATVNFIGGAACLAVPFISPNISWLRRTIAIVGRLAVAIGNETV 441

  Fly   438 YNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITL-LDSFDPKIPAVLFGVVALISGFWVMFLP 501
            ...:.||:||.:||..:.:.|..:.:...:.|.|.. |.|...::|.:::||::::....||.||
Zfish   442 NFANTELYPTPLRNLGVSVCSSASDIGAVVAPFILYRLASIWQELPLLVYGVMSVLYSGLVMLLP 506

  Fly   502 ETMNQPMPESIEDGENFGKGDTWFSQCAGRKKRQNSVYPDDPEQMVPLKNIE 553
            |.....:||:::|.||......       ||::..:.:|:  ..:||:|.:|
Zfish   507 EMKGVDLPETVDDVENLRSRHK-------RKEKDGAQFPE--INIVPMKAVE 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	137/520 (26%)
slc22a3	NP_001107932.1	MFS_SLC22A1_2_3	105..506	CDD:340937	114/412 (28%)