Protein Alignment CG6126 and Slc22a23

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_072146.1
• Gene: Slc22a23 / 64559
• RGDID: 620302
• Length: 689
• Species: Rattus norvegicus
• Alignment Length: 633
• Identity: 157/633 - (24%)
• Similarity: 234/633 - (36%)
• Gaps: 124/633 - (19%)

  Fly     1 MAVDY---VLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDN-- 60
            :.:||   || ..:|.||  |.||.....|..:..|..|....|...:...|...|...|...
  Rat    76 LLLDYDGSVL-PFLGGLG--GGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPNFWCHGAGKGTEL 137

  Fly    61 ---------------SSLSVTPWNSSAILAAIPLKPNGELESCLMFDPSSPGT-NTTINCERYVY 109
                           :|.|.||: |:|.......:.|......|   ||.||. |...|||.:.:
  Rat   138 AGATVTGRWGDMGNWTSPSATPF-STASWGTTSNRSNSSDTPPL---PSPPGKGNNDSNCECHAW 198

  Fly   110 D---TTYYKTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQL 171
            |   .|....:....|:.|||..|...:.:...::|:..|.:..|.:||.|||:.|..:|.:|.|
  Rat   199 DYGIRTGLVQNVVSKWDLVCDNAWKVHVAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSVIFIL 263

  Fly   172 IIGVGVAFIPEYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLV 236
            |.|:.||.......|...|:..|.. .||..:..:.|.:||..|.||.:..:....|...|..|:
  Rat   264 IFGLTVALSVNVTMFSTLRFFEGFC-LAGIILTLYALRIELCPPGKRFIITMVASFVAMAGQFLM 327

  Fly   237 AGWGALIPDRQWLQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVD 301
            .|..||..|.|.||.:......|.|.:|....||.|||....:...|..::.
  Rat   328 PGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLIL------------- 379

  Fly   302 KEYYVQKAKQQAAAEEKSSAGL-----SDLFRTP------------NLRMKTLNVCLCWFANSLV 349
              |..||   ...:.|....|:     .:|.|.|            ||....:.:|:    |||.
  Rat   380 --YLTQK---NCVSPESDIKGVMPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCV----NSLT 435

  Fly   350 YYGLSLSAGK----------LYGNPYLILFIMGLVEFPSYITIVFVLDRLGRR----------SI 394
            .||:.....:          |..|.|...:.|..:...|.:.:..|:..||||          ::
  Rat   436 GYGIHHCFARSMMGHEVKVPLLENFYADYYTMASIALASCLAMCLVVRFLGRRGGLLLFMILTAL 500

  Fly   395 TSTLMLGGGLCCIVAAY-----------IAQGSTTSTAVVMAGKLLIAGSFA------VIYNYSA 442
            .|.|.|  ||..::..|           :|.|.:.|.....:....|.|.||      :...:.|
  Rat   501 ASLLQL--GLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCA 563

  Fly   443 ELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWVMFLPETMNQP 507
            |:.|||:|...:||....|.......|:|.|.:.....:..::|....||....::.|||:.:|.
  Rat   564 EITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQN 628

  Fly   508 MPESIEDGENFGKGDTWFSQCAGRKKRQNSVYPDDPEQMVPLKNIESK 555
            :||:|.:||::              .||..:.....||.:.|.|.|.|
  Rat   629 LPENIANGEHY--------------TRQPLLSHKKGEQPLLLTNAELK 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	138/569 (24%)
Slc22a23	NP_072146.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		7/28 (25%)
		MFS_SLC22A23	187..608	CDD:341002	108/445 (24%)