Protein Alignment CG6126 and SLC22A17

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_065105.3
• Gene: SLC22A17 / 51310
• HGNCID: 23095
• Length: 649
• Species: Homo sapiens
• Alignment Length: 563
• Identity: 145/563 - (25%)
• Similarity: 226/563 - (40%)
• Gaps: 77/563 - (13%)

  Fly     8 EDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLS--LVTVAAVPEHRCFIEGVDNSSLSVTPWNS 70
            |.|:.::|..|..|.||..|..|..|...:.|.|  :.|:|. |.|..:.....|:|....|.|:
Human    81 EALLAQVGALGGGQQLQLGLCCLPVLFVALGMASDPIFTLAP-PLHCHYGAFPPNASGWEQPPNA 144

  Fly    71 SAI-LAAIPLKPNGELESCLMFDPS-----SPGTNTTINC-ERYVYDTTYYKTSRTI-DWNFVCD 127
            |.: :|:..|..:.........|||     .|..|   :| :.:.|:.....|:..| .|:.|||
Human   145 SGVSVASAALAASAASRVATSTDPSCSGFAPPDFN---HCLKDWDYNGLPVLTTNAIGQWDLVCD 206

  Fly   128 RRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARYL 192
            ..|...:.|.:|:||..:|.:.||..||:.||:.:...:.......|||.|........|..|:|
Human   207 LGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFL 271

  Fly   193 LGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIPDRQWLQVIYGLHG 257
            ||.: .||..:..:::.:||..||:|....:..:.|..||..|..|...:..|.::||.:.....
Human   272 LGFL-LAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPC 335

  Fly   258 CLFLGHWW---WLDESPRWLWMQGRAAEA---VDIVAKGLRINGSGIPVDKEYYVQKAKQQAAAE 316
            .|||.:.|   :| ||.|||.::.:..||   :.|:|:..|.:|..:..:.:..:|..:......
Human   336 ILFLFYGWPGLFL-ESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLP 399

  Fly   317 EKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLV------------------YYGLSLSAGKLYGN 363
            ..||...:.|.   |.|....|:.:..|.|.:.                  :|..||.|.   |.
Human   400 ATSSFSFASLL---NYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLAS---GT 458

  Fly   364 PYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIV-------------AAYIAQG 415
            ..|....:|:           .:||.|||.|....|...|:..:|             ..:..||
Human   459 AALACVFLGV-----------TVDRFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQG 512

  Fly   416 S----TTSTAVVMAGKL-LIAGSFAVIYN--YSAELFPTVVRNSAMGLGSMCARLSGALTPLITL 473
            :    ....|:.....| |.:...|.|.:  .:||:.||.||...:||......|.|...|...|
Human   513 NPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRL 577

  Fly   474 LDSFDPKIPAVLFGVVALISGFWVMFLPETMNQPMPESIEDGE 516
            .......:..|:....||:....:|.||||..:.:||.:.|||
Human   578 HMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGE 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	138/548 (25%)
SLC22A17	NP_065105.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..70
		MFS_SLC22A17	174..605	CDD:341003	110/452 (24%)