Protein Alignment CG6126 and slc22a4

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_957143.1
• Gene: slc22a4 / 393822
• ZFINID: ZDB-GENE-040426-1517
• Length: 553
• Species: Danio rerio
• Alignment Length: 540
• Identity: 165/540 - (30%)
• Similarity: 260/540 - (48%)
• Gaps: 52/540 - (9%)

  Fly     4 DYVLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFI-EGVDNSSLSVTP 67
            ||  :|:...||.:|.:|...|....:|.|..|...|.:|.|...|.|.|.| |.::.||:
Zfish     3 DY--DDITSFLGTWGPFQLTVFLALAISILPNGFVGLYIVFVGDTPAHECLIPEQINISSV---- 61

  Fly    68 WNSSAILAAIPLK-PNGELE--SC-------------LMFDPSSPGTNTTINCERYV----YDTT 112
            |..    ||||.: .:|.|:  ||             |.:.|:.....:.|..|..|    |...
Zfish    62 WRD----AAIPTQMQDGVLKRSSCSRYRLDTLRQLSMLNYTPNVEVNLSQIETEPCVDGWSYSQE 122

  Fly   113 YYKTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGV 177
            :|:::...:|:.||:|.:.|.:..:::..||..|....|.::|:.||:.|.......|.|..:..
Zfish   123 FYQSTIVTEWDLVCEREYKGPLTSSIYFCGVLVGTFLSGQMSDRYGRRPVLFTMMALQTITILIQ 187

  Fly   178 AFIPEYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGAL 242
            .|.|.:..|....:.:|..|.:. |:..:||..|::.|..|.:.|       :.|:.:.:|.|.:
Zfish   188 MFSPSWEVFSAIYFFVGFSGFSN-YVVAYVLGSEILSPASRVLFG-------SLGVFMGSGIGQM 244

  Fly   243 --------IPDRQWLQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIP 299
                    |...:||.:...|.|.|:...||::.||||||..|||.|||..::.:....|....|
Zfish   245 FFPLAAYFIRSWRWLVLTNALTGLLYFPLWWFIPESPRWLLSQGRTAEAEAVLRRAAEKNRVTAP 309

  Fly   300 VDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVC-LCWFANSLVYYGLSLSAGKLYGN 363
              :..:.....::||.:......:.|:....| .:.|:.:| |.|...::.||.|.|:...|:||
Zfish   310 --EVIFSSSEIEEAAKKRIQKHSILDILSNCN-AVSTILICSLLWMVITMSYYALILNTTNLHGN 371

  Fly   364 PYLILFIMGLVEFPSYITIVFVLDRLGRRSI-TSTLMLGGGLCCIVAAYIAQGSTTSTAVVMAGK 427
            |||..|:..:||.|:||....:|....||.. .|||:|||.|..|:.....:....:||:.|.||
Zfish   372 PYLNFFLSAVVEVPAYIIAALLLRFCSRRICQASTLLLGGALIFIIQLIPTELQGLATALEMLGK 436

  Fly   428 LLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALI 492
            |.:..:|.|:|..::|||||||||.|||..||.||:...::|.|..|.::...||.::.|.:||.
Zfish   437 LCVTAAFCVVYAVTSELFPTVVRNMAMGSCSMTARIGSIISPFIIYLGNYYRYIPYIVIGGLALF 501

  Fly   493 SGFWVMFLPETMNQPMPESI 512
            ||...:.|||:..:.:||:|
Zfish   502 SGVMSLLLPESKGKVLPETI 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	158/525 (30%)
slc22a4	NP_957143.1	MFS_SLC22A4_5_OCTN1_2	106..510	CDD:340934	127/414 (31%)