Protein Alignment CG6126 and Slc22a20

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_941052.1
• Gene: Slc22a20 / 381203
• MGIID: 2685809
• Length: 556
• Species: Mus musculus
• Alignment Length: 558
• Identity: 181/558 - (32%)
• Similarity: 274/558 - (49%)
• Gaps: 46/558 - (8%)

  Fly     9 DLMGKLGEFGKYQFLQFFLQVL-SGLTAGMHMLSLVTVAAVPEHRC-----FIEGVDNSSLSVTP 67
            ||:..||..|::|.:...|.:| .||.|....|...| ||.|.|.|     :.|...|.|   ..
Mouse     5 DLLDALGGVGRFQLVYTALLLLPCGLLACHTFLQNFT-AAAPPHHCQHPANYTEPTTNVS---GV 65

  Fly    68 WNSSAILAAIPLKPNGELESCLMF----------DPSSPGTNTTINCERYVYDTTYYKTSRTIDW 122
            |    :.|||||..:|:.|.|..:          :.||.|..|....:.:|||.:.:.::..::|
Mouse    66 W----LRAAIPLNQHGDPEPCRRYVEPQWALLKPNASSHGVATEGCKDGWVYDRSIFPSTIVMEW 126

  Fly   123 NFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFM 187
            :.||:.|.:..:.|:::|.||..||...|||||::|||....||.|...:.|...|::..:.::.
Mouse   127 DLVCEARTLRDLAQSIYMSGVLVGAALFGGLADRLGRKAPLVWSYLQLAVSGAATAYVGSFSAYC 191

  Fly   188 VARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIPDRQWLQVI 252
            |.|:|:|:..| |..:....|.:|.:....|||.||.....|..|.:::||...||...:|||..
Mouse   192 VFRFLMGMTFS-GIILNSLSLVVEWMPTRGRTVAGILLGFSFTLGQLILAGVAYLIRPWRWLQFA 255

  Fly   253 YGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRING---SGIPVDKEYYVQKAKQQAA 314
            ......:|..:.|||.||.|||.:.|:|.:||..:.|...:||   .|..:..| .|....|...
Mouse   256 VSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLQKVAMMNGRKAEGERLTTE-VVSSYIQDEF 319

  Fly   315 AEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVEFPSY 379
            |..::|..:.||||||.:|..|..:...||:||:.||||::...|...:.||:..:.|:::.|:.
Mouse   320 ASVRTSNSILDLFRTPAIRRVTCCLMGVWFSNSVAYYGLAMDLQKFGLSIYLVQALFGIIDIPAM 384

  Fly   380 ITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQG-STTSTAVVMAGKLLIAGSFAVIYNYSAE 443
            :.....:..:|||:..|:.::..||..|...::.:. .|..|.....||..:|.||..:|.::.|
Mouse   385 LVATTTMIYVGRRATVSSFLILAGLMVIANMFMPEDLQTLRTVQAALGKGCLASSFICVYLFTGE 449

  Fly   444 LFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWV-MFLPETMNQP 507
            |:||.:|...||..|:.|||.|.:.||||.|....|.:|.|.||..::::|..| .||.||.|.|
Mouse   450 LYPTEIRQMGMGFASVNARLGGLVAPLITTLGEISPVLPPVSFGATSVLAGMAVACFLTETRNVP 514

  Fly   508 MPESIEDGENFGKGDTWFSQCAGRKKRQNSVYPDDPEQ 545
            :.|:|...|...|        .||.||       |.||
Mouse   515 LVETIAAMERRVK--------QGRSKR-------DTEQ 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	167/515 (32%)
Slc22a20	NP_941052.1	MFS_SLC22A6_OAT1_like	103..508	CDD:341004	132/406 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..556		8/27 (30%)