Protein Alignment CG6126 and Slc22a21

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_008765965.1
• Gene: Slc22a21 / 303140
• RGDID: 1561735
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 555
• Identity: 167/555 - (30%)
• Similarity: 265/555 - (47%)
• Gaps: 75/555 - (13%)

  Fly     4 DYVLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPW 68
            ||  ::|...|||:|.:|.|.|||...|.:..|...||.|.:.|.|||||.:....|.|   :.|
  Rat     3 DY--DELTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSAVFLTASPEHRCLVPDTVNLS---SAW 62

  Fly    69 NSSAI------------------------LAAIPLKPNG-------ELESCLMFDPSSPGTNTTI 102
            .:.:|                        .:|:.|:|..       |||:||
  Rat    63 RNHSIPLEMKDGRQVPHKCRRYRLATIANFSALGLEPGEDVDLKQLELENCL------------- 114

  Fly   103 NCERYVYDTTYYKTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSA 167
              :.:.|....:.::...:||.||:..|...:..::|.:||..|:...|.|:|:.|||.|..|:
  Rat   115 --DGWEYSKEVFLSTIVTEWNLVCNDAWKAPLTTSMFYVGVLLGSFISGQLSDRFGRKPVLFWT- 176

  Fly   168 LFQLIIGVGVAFIP------EYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTV---CGI 223
               :.:..|.:|:.      |.|:.:.|  |:| :|....|:..|||..|::..:.|.:   .||
  Rat   177 ---MGMHTGFSFLQVFSVNFEMFTLLFA--LVG-MGHISNYVAAFVLGTEILSKSIRIIFATLGI 235

  Fly   224 TFQAVFAGGIMLVAGWGALIPDRQWLQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVA 288
            ..  .||.|.|::..:...|.|.:.|.:...|.|.|....||::.||||||..|||..||..|:.
  Rat   236 CI--FFAFGFMVLPLFAYFIRDWRMLLMAITLPGVLCGALWWFIPESPRWLISQGRVKEAEVIIR 298

  Fly   289 KGLRINGSGIP---VDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVY 350
            |..:.||...|   .|......  .|...|:...|..:.||.||.|:|:.|:...:.|...|:.|
  Rat   299 KAAKFNGIVAPSTIFDPSETTN--LQDGNAKNTQSHHIYDLVRTRNIRILTIMSIILWLTISVGY 361

  Fly   351 YGLSLSAGKLYGNPYLILFIMGLVEFPSYITIVFVLDRLGRR-SITSTLMLGGGLCCIVAAYIAQ 414
            :||||....|.||.|:..|::..||.|:|:....:|..:.|| |:..:|.|||.:..|:....:.
  Rat   362 FGLSLDTPNLNGNIYVNGFLLAAVEVPAYVLAWLLLQHVTRRYSMAGSLFLGGSVLLILQLVPSD 426

  Fly   415 GSTTSTAVVMAGKLLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDP 479
            ....|||:||.||..|..:::::|.|:|||:||||||..:|:.|..:||...|:|....|.::|.
  Rat   427 LLYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDR 491

  Fly   480 KIPAVLFGVVALISGFWVMFLPETMNQPMPESIED 514
            .:|.::.|.:.:::.....|.||:....:|::|::
  Rat   492 HLPYIVMGSLTILTAIITFFFPESSGVSLPDTIDE 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	161/538 (30%)
Slc22a21	XP_008765965.1	2A0119	12..523	CDD:273328	162/539 (30%)