Protein Alignment CG6126 and Slc22a12

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 542
• Identity: 161/542 - (29%)
• Similarity: 269/542 - (49%)
• Gaps: 52/542 - (9%)

  Fly     7 LEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVT---PW 68
            |.|.:|.||.|..:|.:.....:|...|  .:||...: ||||.|||::..:|||:...:   ..
Mouse     6 LLDRVGGLGRFQLFQTVALVTPILWVTT--QNMLENFS-AAVPHHRCWVPLLDNSTSQASIPGDL 67

  Fly    69 NSSAILA-AIPLKPNGELESCLMF--------DPSSPGTN----TTINCE-RYVYDTTYYKTSRT 119
            ....:|| :||..|:.:...||.|        :.::..||    .|..|| .:|||.:.::::..
Mouse    68 GPDVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATATNWSDAATEPCEDGWVYDHSTFRSTIV 132

  Fly   120 IDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEY- 183
            ..|:.||:.:.:..:.|::|:.|:..||...|..:|:.||:.|..||.|...:.|...||:|.:
Mouse   133 TTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTAAAFMPTFP 197

  Fly   184 ----FSFMVARYLLGIVGSAGAYIC------GFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAG 238
                |.|::|..:.|::.:..:.:.      |..|.|.|      ...|.:|..|..|.:    .
Mouse   198 LYCLFRFLLASAVAGVMMNTASLLMEWTSAQGSPLVMTL------NALGFSFGQVLTGSV----A 252

  Fly   239 WGALIPDRQW--LQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRIN---GSGI 298
            :|.    |.|  ||:.......||..:.|||.||.|||...|:..:.:..:.:...:|   ..|.
Mouse   253 YGV----RSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAAVNRRKAEGD 313

  Fly   299 PVDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGN 363
            .:..| .::.|.::..:.:|:.|.|..|..||.||.:|:...|||||....:|||:|....|..|
Mouse   314 TLTME-VLRSAMEEEPSRDKAGASLGTLLHTPGLRHRTIISMLCWFAFGFTFYGLALDLQALGSN 377

  Fly   364 PYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQG-STTSTAVVMAGK 427
            .:|:..::|:|:||.....:.::.|||||....:.::..|||.:....:..| ....:|:.:.|.
Mouse   378 IFLLQALIGIVDFPVKTGSLLLISRLGRRLCQVSFLVLPGLCILSNILVPHGMGVLRSALAVLGL 442

  Fly   428 LLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALI 492
            ..:.|:|..|..:|:||||||:|.:|:||..:.||....|.||:.||..:...:|.:::|||.::
Mouse   443 GCLGGAFTCITIFSSELFPTVIRMTAVGLCQVAARGGAMLGPLVRLLGVYGSWMPLLVYGVVPVL 507

  Fly   493 SGFWVMFLPETMNQPMPESIED 514
            ||...:.||||.|.|:|::|:|
Mouse   508 SGLAALLLPETKNLPLPDTIQD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	154/528 (29%)
Slc22a12	NP_033229.3	MFS_OAT	109..516	CDD:340932	121/421 (29%)