Protein Alignment CG6126 and Slc22a5

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_035526.1
• Gene: Slc22a5 / 20520
• MGIID: 1329012
• Length: 557
• Species: Mus musculus
• Alignment Length: 548
• Identity: 164/548 - (29%)
• Similarity: 267/548 - (48%)
• Gaps: 66/548 - (12%)

  Fly     4 DYVLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPW 68
            ||  :::...|||:|.:|.|.|||...|.:..|.:.:|:|.:|..|||||.:....|.|   :.|
Mouse     3 DY--DEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVPHTVNLS---SAW 62

  Fly    69 NSSAI------------------LAAIP------LKPNG-------ELESCLMFDPSSPGTNTTI 102
            .:.:|                  ||.|.      |:|..       |.||||
Mouse    63 RNHSIPLETKDGRQVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQESCL------------- 114

  Fly   103 NCERYVYDTTYYKTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSA 167
              :.:.||...:.::...:|:.||...|...:..::|.:||..|:...|.|:|:.|||.|
Mouse   115 --DGWEYDKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNV----- 172

  Fly   168 LFQLIIGV--GVAFIPEY---FSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQA 227
            || |.:|:  |.:|:..:   |......::|..:|....|:..|||..|::..:.|.:.......
Mouse   173 LF-LTMGMQTGFSFLQVFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVC 236

  Fly   228 VF-AGGIMLVAGWGALIPDRQWLQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGL 291
            :| |.|.|::..:...|.|.:.|.:...:.|.|....||::.||||||..|||..||..|:.|..
Mouse   237 IFYAFGFMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAA 301

  Fly   292 RINGSGIPVDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLS 356
            :||  ||......:.....|...:.:.....:.||.||.|:|:.|:...:.|...|:.|:||||.
Mouse   302 KIN--GIVAPSTIFDPSELQDLNSTKPQLHHIYDLIRTRNIRVITIMSIILWLTISVGYFGLSLD 364

  Fly   357 AGKLYGNPYLILFIMGLVEFPSYITIVFVLDRLGRR-SITSTLMLGGGLCCIVAAYIAQGSTTST 420
            ...|:|:.|:..|::..||.|:|:....:|..|.|| ||::.|.|||.:...:....::....||
Mouse   365 TPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQYLPRRYSISAALFLGGSVLLFMQLVPSELFYLST 429

  Fly   421 AVVMAGKLLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVL 485
            |:||.||..|..:::::|.|:|||:||||||..:|:.|..:||...|:|....|.::|..:|.:|
Mouse   430 ALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYIL 494

  Fly   486 FGVVALISGFWVMFLPETMNQPMPESIE 513
            .|.:.:::....:|.||:...|:|::|:
Mouse   495 MGSLTILTAILTLFFPESFGVPLPDTID 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	159/532 (30%)
Slc22a5	NP_035526.1	2A0119	12..520	CDD:273328	160/533 (30%)