Protein Alignment CG6126 and Slc22a3

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_035525.1
• Gene: Slc22a3 / 20519
• MGIID: 1333817
• Length: 551
• Species: Mus musculus
• Alignment Length: 563
• Identity: 172/563 - (30%)
• Similarity: 276/563 - (49%)
• Gaps: 53/563 - (9%)

  Fly     8 EDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEH-------------RCFIEGVD 59
            :..:.|.||||::|...|.|..|:|:|.....:.:|.:.:.|::             ||
Mouse     5 DQALRKAGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGSQPDYYWCRGPRATALAERC------ 63

  Fly    60 NSSLSVTP---WNSSAILAAIPLKPNGELESCLMFDPSSPGTNTTINCERYVY------------ 109
                :.:|   ||.:.....:|.:..|: ..|..:...:..|::.::|:....
Mouse    64 ----AWSPEEEWNLTTPELHVPAERRGQ-GHCHRYLLEATNTSSELSCDPLTAFPNRSAPLVSCS 123

  Fly   110 -DTTYYKTSRTI--DWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQL 171
             |..|.:|..||  .::.||...||..:.|.:..||...||.|||..||:.||..::..|.....
Mouse   124 GDWRYVETHSTIVSQFDLVCSNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIIYLISCFGVG 188

  Fly   172 IIGVGVAFIPEYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLV 236
            |.||.|||.|.:..|::.|:|.|:.|. ||::..||:..|:||..:|.:.||..|..|..||:::
Mouse   189 ITGVVVAFAPNFSVFVIFRFLQGVFGK-GAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIIL 252

  Fly   237 AGWGALIPDRQWLQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVD 301
            .|.....|..|.:|:...|...|||.::|.:.||||||..:.:..:|:.|:.:..:.||
Mouse   253 PGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNG------ 311

  Fly   302 KEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYL 366
            |......::.....||.|:....||.|||.:|..||.:...||.:::||.||.:..|.:.||.|:
Mouse   312 KHLSSNYSEITVTDEEVSNPSCLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIGGNLYI 376

  Fly   367 ILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQG-STTSTAVVMAGKLLI 430
            ..||.||||.|..:.|:..::|||||...:...:..|:.|:|.|::.:| ....|.|...|:|.|
Mouse   377 DFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEGIPWLRTTVATLGRLGI 441

  Fly   431 AGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTP-LITLLDSFDPKIPAVLFGVVALISG 494
            ..:|.::|..::||:||.:||..:.|.|......|.:.| |:..|.:...::|.::||::|.:.|
Mouse   442 TMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAIWLELPLIIFGILASVCG 506

  Fly   495 FWVMFLPETMNQPMPESIEDGENFGKGDTWFSQCAGRKKRQNS 537
            ..||.||||....:||::||.|..|...  ..||..:||.|.|
Mouse   507 GLVMLLPETKGIALPETVEDVEKLGSSQ--LHQCGRKKKTQVS 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	159/527 (30%)
Slc22a3	NP_035525.1	2A0119	12..523	CDD:273328	160/528 (30%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O75751	284..288		2/3 (67%)