Protein Alignment CG6126 and Slc22a25

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_620263.1
• Gene: Slc22a25 / 192273
• RGDID: 621104
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 581
• Identity: 152/581 - (26%)
• Similarity: 267/581 - (45%)
• Gaps: 93/581 - (16%)

  Fly     8 EDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCF--------IEGVDNSSLS 64
            :||:.::|..|::|.||....::..:....|.|.....|.:|.|||:        :.|.||.:||
  Rat     4 QDLLNQVGSLGRFQILQMTFILIFNIIISPHSLLENFTAVIPNHRCWVPILDNDTVSGNDNGNLS 68

  Fly    65 VTPWNSSAILAAIPLKPNGELESCLMF---------------DPSSPGTNTTINCERYVYDTTYY 114
                ....:..:|||..:...|.|..|               ..:.|.|...:  :.:|||.:.:
  Rat    69 ----QDDLLRVSIPLDSDLRPEKCRRFVQPQWDLLHLNGTFSSVTEPDTEPCV--DGWVYDQSTF 127

  Fly   115 KTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAF 179
            .::...:|:.||:.:.:.:|.:.:|:.|:..|.:..|.|.|:.||:.:...::|...:.....||
  Rat   128 LSTIITEWDLVCESQSLDSIAKFLFLTGILVGNILYGPLTDRFGRRLILICASLQMAVTETCAAF 192

  Fly   180 IPEYFSFMVARYLLGI------VGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAG 238
            .|.:..:...|:|.||      ..||       :|.:|...|        .|||: |.|::|.||
  Rat   193 APTFLIYCSLRFLAGISFSTVLTNSA-------LLIIEWTRP--------KFQAL-ATGLLLCAG 241

  Fly   239 -------WGALIPDRQWLQVIYGLHGCLFLGHWW------WLDESPRWLWMQGRAAEAVDIVAKG 290
                   .|.....|.|    :.||..:.:..::      ||.||.|||.|..:..:.:..:.|.
  Rat   242 AIGQTVLAGLAFTVRNW----HHLHLAMSVPIFFLLVPTRWLSESARWLIMTNKLQKGLKELIKV 302

  Fly   291 LRING-----SGIPVDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVY 350
            ..|||     ..:.::....:.| ::..|::.|||  |.|||||||||.:...:.|..|...|..
  Rat   303 AHINGMKNSTDVLTIEVVRTIMK-EELEASQTKSS--LWDLFRTPNLRKRICLLSLVRFVVWLSV 364

  Fly   351 YGLSLSAGKLYGNPYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQG 415
            .||.::...|..|.:|:..::|::..|:.:..:|:::.||||.....::...|:..:...::.|.
  Rat   365 IGLLINFQHLRINVFLLQCLLGIITIPANLVGIFLVNHLGRRISQLFIISLFGISILAIIFVPQE 429

  Fly   416 STTSTAVVMAGKLLIAGSFAVIYNYSA-----ELFPTVVRNSAMGLGSMCARLSGALTPLITLLD 475
            ......|:..    ..|.|:.:...||     ||.||::|.:|:|:..:......||:||..:|.
  Rat   430 MQILRMVLAT----FGGVFSFVSVSSALVHANELLPTIIRATALGVIGIAGSTGAALSPLFMILR 490

  Fly   476 SFDPKIPAVLFGVVALISGFWVMFLPETMNQPMPESIEDGENFGKGDTWFSQCAGRKKRQN 536
            ::...:|.:::||::.:.|..|:.||||.|||:|:||:|.||.|:        |.|:.:||
  Rat   491 TYSDSLPWIIYGVLSFLGGLVVLLLPETKNQPLPDSIQDVENEGR--------ASRQGKQN 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	139/546 (25%)
Slc22a25	NP_620263.1	MFS_OAT	109..506	CDD:340932	107/425 (25%)