Protein Alignment CG6126 and SVOPL

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001132928.1
• Gene: SVOPL / 136306
• HGNCID: 27034
• Length: 492
• Species: Homo sapiens
• Alignment Length: 543
• Identity: 111/543 - (20%)
• Similarity: 204/543 - (37%)
• Gaps: 152/543 - (27%)

  Fly     5 YVLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWN 69
            :.:||.:..:| ||::....|.:...:|:...|.::.:..|:.|
Human    32 FTVEDAVETIG-FGRFHIALFLIMGSTGVVEAMEIMLIAVVSPV--------------------- 74

  Fly    70 SSAILAAIPLKPNGELESCLMFDPSSPGTNTTINCERYVYDTTYYKTSRTIDWNFVCDRRWMGAI 134
                                            |.||                |..   ..|..|:
Human    75 --------------------------------IRCE----------------WQL---ENWQVAL 88

  Fly   135 VQTVFMLGVFTGAVTLGGLADKVGRKTV----FCWSALFQLIIGVGVAFIPEYFSFMVARYLLGI 195
            |.|:...|....::..|.|||:.||..:    |.|.|.|.|:    .:|.|.|..|:..|.::|
Human    89 VTTMVFFGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLL----TSFAPSYIWFVFLRTMVG- 148

  Fly   196 VGSAGAYICGFVLTMELVGPTKRTVCGITFQAVF--AGGIMLVAGWGALIP--DRQWLQVIYGLH 256
            .|.:| :..|.::..|.: |||.....:....||  ||.::::.....:||  ..:||..:..:.
Human   149 CGVSG-HSQGLIIKTEFL-PTKYRGYMLPLSQVFWLAGSLLIIGLASVIIPTIGWRWLIRVASIP 211

  Fly   257 GCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDK--EYYVQKAKQQAAAEEKS 319
            |.:.:..:.::.||.|:....|....|:..:.:..::|.|.:|..|  |..::|..:
Human   212 GIILIVAFKFIPESARFNVSTGNTRAALATLERVAKMNRSVMPEGKLVEPVLEKRGR-------- 268

  Fly   320 SAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLY----------------------- 361
               .:||.....|| .||.:.:.|...|..|||:.|::.:|.
Human   269 ---FADLLDAKYLR-TTLQIWVIWLGISFAYYGVILASAELLERDLVCGSKSDSAVVVTGGDSGE 329

  Fly   362 -----------GNPYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQG 415
                       .:.|..:.|..:.|.......:..::.|||| ::.::.:|    |....::...
Human   330 SQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRR-LSLSITMG----CTALFFLLLN 389

  Fly   416 STTSTAVVMAG----KLLIAGSFAVIYNYSAELFPTVVRNSAMGL-GSMCARLSGALTPLITLLD 475
            ..||:|.::..    :.|:|.:|..:|.|:||::||.:|...||. ||:| |:...:.|.|:.:
Human   390 ICTSSAGLIGFLFMLRALVAANFNTVYIYTAEVYPTTMRALGMGTSGSLC-RIGAMVAPFISQV- 452

  Fly   476 SFDPKIPAVLFGVVALISGFWVM 498
                .:.|.:.|.:.|.|...|:
Human   453 ----LMSASILGALCLFSSVCVV 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	109/533 (20%)
SVOPL	NP_001132928.1	MFS_SVOPL	49..480	CDD:341000	106/525 (20%)