Protein Alignment CG6126 and sv2b

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_002933355.1
• Gene: sv2b / 100497731
• XenbaseID: XB-GENE-6041859
• Length: 711
• Species: Xenopus tropicalis
• Alignment Length: 682
• Identity: 129/682 - (18%)
• Similarity: 212/682 - (31%)
• Gaps: 280/682 - (41%)

  Fly     5 YVLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWN 69
            |..|:::.:.|. |::|:..|.:..|:.:..|:.:              |:.|.
 Frog   121 YQYENIIQECGH-GRFQWTLFVVLGLALMADGVEV--------------FVVGF----------- 159

  Fly    70 SSAILAAIPLKPNGELESCLMFDPSSPGTNTTINCERYVYDTTYYKTSRTIDWNFVCDRRWMGAI 134
                     :.|:.|.:.||                           ||:       ::..:|.|
 Frog   160 ---------VLPSAEKDMCL---------------------------SRS-------NKGMLGLI 181

  Fly   135 VQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARYLLGIVGSA 199
            |    .||:..||...||||||||||.....|...........:|:..|..|:..|.:.|. |..
 Frog   182 V----YLGMMLGAFVWGGLADKVGRKKCLIISLTINAAFSFVSSFVQGYGLFLFCRLISGF-GIG 241

  Fly   200 GAYICGFVLTMELVGPTKR-----TVC-----GITFQAVFAGGIMLVAGWGALIPDRQWLQVIYG 254
            |:....|....|.:...||     .:|     |..:.|..|..|:...|||..:          |
 Frog   242 GSLPIVFAYFSEFLAREKRGEHLSWLCMFWMIGAVYAAAMAWSIIPHYGWGFSM----------G 296

  Fly   255 LHGCLFLGHWW-------------------WLDESPRWLWMQGRAAEAVDIVAK----GLRINGS 296
            .|   :..|.|                   ::.||||:|...|:..||..|:..    .:|..|.
 Frog   297 TH---YHFHSWRVFVVICVLPCIASIIALKFMPESPRFLLETGKHDEAWMILKNIHDTNMRAKGE 358

  Fly   297 GIPVDKEYYVQKAKQ-QAAAEEKSSAG-------------LSDLFR------TPNLRMKTLNVCL 341
            ...|....:::..|| ....|.:||.|             :..::.      :...|..|:.:.:
 Frog   359 PEKVFTVSHIKTPKQPDEFIEIQSSTGTWFQRWFVRIMTVIKQIWENMLHCFSGQFRKNTIFLAV 423

  Fly   342 CWFANSLVYYGLSL--------------------------------------------------- 355
            .||..||.||||::
 Frog   424 VWFTMSLSYYGLTVWFPDTIRYLQDEDYASKVKRFTDENVKNFNFNFTLENQIHEDGEYYNDRFY 488

  Fly   356 -----------------------SAGKLYGN------------------------------P--- 364
                                   |.|.::.|                              |
 Frog   489 KMKLKYVTFKDSLFDECYFEDVTSTGSIFENCTIQNTVFYNTDLYQHKFIDCNFINVTFSQPKEG 553

  Fly   365 -------------YLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQGS 416
                         ||:.|:..|...|..|....::|::||..:.:..||...:||.   ::..|:
 Frog   554 CHIDFEEDNDFLIYLVSFLGSLSVLPGNIISALLMDKIGRIRMIAGSMLISAVCCF---FLFFGN 615

  Fly   417 TTSTAVVMAGKLLIAGSFAVIYN----YSAELFPTVVRNSAMG-LGSMC--ARLSGALTPLITLL 474
              |.:.::..:.|..|:....:|    .:.||:||..|.:|.| |..:|  |.:.|.     ::.
 Frog   616 --SESAMIGWQCLFCGTSIAAWNALDVVTVELYPTNKRATAFGILNGLCKLAAIFGN-----SIF 673

  Fly   475 DSF--DPKIPAVLFGVVALISGFWV-MFLPET 503
            .||  ..|:..:|....||:.|..: :.||||
 Frog   674 ASFVGITKVIPILLASTALVGGGLISLRLPET 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	127/672 (19%)
sv2b	XP_002933355.1	synapt_SV2	1..711	CDD:130366	129/682 (19%)