Protein Alignment CG6126 and slc22a23

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_002936473.1
• Gene: slc22a23 / 100491610
• XenbaseID: XB-GENE-966989
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 635
• Identity: 163/635 - (25%)
• Similarity: 248/635 - (39%)
• Gaps: 152/635 - (23%)

  Fly     1 MAVDY---VLEDLMGKLGEFGK---------------YQFLQFFL--------QVLSGLTAGMHM 39
            :.:||   || ..:|.||.:.|               .||..|||        ||.|  :.|.|.
 Frog    54 LLLDYDGSVL-PFLGGLGSYNKRLVLLTWIPALFLSFSQFSDFFLLDQPDKWCQVNS--SGGEHG 115

  Fly    40 LSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSSAILAAIPLKPNGELESCLMFDPSSP----GTNT 100
            ...|           :..|.|.|       |..:|    |.|..:|       |::|    .||.
 Frog   116 PGRV-----------VSHVGNDS-------SGGLL----LLPPPQL-------PTTPTPTSATNY 151

  Fly   101 TINCERYVYDTTYYKTSRTI------DWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGR 159
            |.:|....:|   |:....:      .|:.|||..|...|.:...::|:..|.:..|.:||.:||
 Frog   152 TDSCLCTKWD---YRIRAGLVQNVVSKWDLVCDSSWKVHIAKFSLLVGMIFGYLITGCVADWIGR 213

  Fly   160 KTVFCWSALFQLIIGVGVAFIPEYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGIT 224
            :.|...|.:|.||.|:.||...:...|...|:..|.. .||..:..:.|.:||..|..|.:  ||
 Frog   214 RLVLLISVIFNLIFGLTVALSVDVNMFSTLRFFEGFC-LAGIILSLYALRIELCPPGHRFM--IT 275

  Fly   225 FQAVFAG--GIMLVAGWGALIPDRQWLQVIYGLHGCLFLGHWWWLDESPRWLW--MQGRAA--EA 283
            ..|.|.|  |..|:.|..||..|.|.||.:......|.|.:|....||.|||.  ||..|:  :.
 Frog   276 MVASFIGMAGQFLLPGIAALCRDWQVLQAVIICPFILMLFYWVIFPESLRWLMATMQFDASKKQI 340

  Fly   284 VDIVAKGLRIN------GSGIPVDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLC 342
            :.::.:. |:|      |....:::|.|.:..|          ..:..:..|.||....|.:|:
 Frog   341 LKMIHRN-RVNMESDVKGVMPELEREVYTRPKK----------VCIVKVVGTRNLWKNILVLCV- 393

  Fly   343 WFANSLVYYGLSLSAGKLYGNP----------YLILFIMGLVEFPSYITIVFVLDRLGRR----- 392
               |||..||:.....|...:|          |:..|.|..:...|.:.:..|:..||||
 Frog   394 ---NSLTGYGIHHCFAKSLMDPELNTSFMHNFYVNYFAMAGITLASCLAMCPVVGFLGRRGGLLL 455

  Fly   393 -----SITSTLMLGGGLCCIVAAYIAQGSTTSTAVVMAGKLLI------------AGSFAVIYNY 440
                 ::.|.|.|  ||..::..| :|...|..:.::..|..|            .||.:|.  :
 Frog   456 FMILTALASLLQL--GLLNLIGKY-SQRPETGLSDIVKNKFSIIFSIIGMFSSHAVGSLSVF--F 515

  Fly   441 SAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWVMFLPETMN 505
            .||:.|||:|...:||....|.......|::.|.:.....:..::|....||....::.|||:.|
 Frog   516 CAEITPTVIRGGGLGLVLASAGFGSLTAPIMELHNQKGYFLHHIIFACCTLICIICILLLPESKN 580

  Fly   506 QPMPESIEDGENFGKGDTWFSQCAGRKKRQNSVYPDDPEQMVPLKNIESK 555
            |.:||:|.:||::              .||..:.....||.:.|.|.|.|
 Frog   581 QNLPENIPEGEHY--------------TRQPLLSHRKGEQPLLLTNSELK 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	144/571 (25%)
slc22a23	XP_002936473.1	MFS_SLC22A23	149..562	CDD:341002	113/438 (26%)