Protein Alignment CG6126 and slc22a8

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_002937554.2
• Gene: slc22a8 / 100490266
• XenbaseID: XB-GENE-22061134
• Length: 556
• Species: Xenopus tropicalis
• Alignment Length: 529
• Identity: 170/529 - (32%)
• Similarity: 274/529 - (51%)
• Gaps: 29/529 - (5%)

  Fly     9 DLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIE--GVDNSSLSVTPWNSS 71
            :|:.:.|..|::|..|..|.....|....|.|.....||:|:|:|...  |..::|...|.:..
 Frog     5 ELLERTGGMGRFQITQVVLLCFPILLMASHNLLQNFSAAIPDHKCKANDTGYQSNSTDETGYER- 68

  Fly    72 AILAAIPLKPNGELESCLMF---DPSSPGTNTTIN---------CE-RYVYDTTYYKTSRTIDWN 123
              |:| ||..||:.:.||.:   .....|:|:|.|         |. .:.|....:.::...:|:
 Frog    69 --LSA-PLDANGQPDRCLEYVEIQWRMVGSNSTWNNSSELATRPCTIGWEYSKDEFSSTIITEWD 130

  Fly   124 FVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLII-GVGVAFIPEYFSFM 187
            .||.|:....:.|:::|.||..||:.||||:|:.||:.:..|| .|||.: ||..||.|.|.|:.
 Frog   131 LVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWS-YFQLAVSGVCAAFSPNYLSYC 194

  Fly   188 VARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIPDRQWLQVI 252
            :.|:|.|:..| |..:....|.:|.|....|||.|......:..|.:|:||....:.|.:|||:.
 Frog   195 IFRFLTGMALS-GIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLC 258

  Fly   253 YGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDK----EYYVQKAKQQA 313
            ..|...::..:.||..||.|||.:.|:..:||..:.|...:||.....:|    ....:..|:.|
 Frog   259 VSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEKITLESLKSEMIKELA 323

  Fly   314 AAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVEFPS 378
            :|  |||..:.||.||..:|..:..:.|.||:.|..||||::...|...:.|||..|.|.|:||:
 Frog   324 SA--KSSYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPA 386

  Fly   379 YITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIA-QGSTTSTAVVMAGKLLIAGSFAVIYNYSA 442
            .:.....:..:||:......::.||:..|...::. :..|..|::.:.||..:|.||:.|:.|:.
 Frog   387 KLVSATAMIYVGRKFTQFMSLILGGIAIIANIFVPNELQTVRTSLAVFGKGCLAASFSCIFLYTT 451

  Fly   443 ELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWVMFLPETMNQP 507
            ||:|||:|.|.:|:.|..||:.|.:.||:.:|....|.:|.:::|...:|||..|.|||||:|:|
 Frog   452 ELYPTVIRQSGLGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVFFLPETVNKP 516

  Fly   508 MPESIEDGE 516
            :|::||:.|
 Frog   517 LPDTIEEVE 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	165/515 (32%)
slc22a8	XP_002937554.2	MFS_SLC22A6_OAT1_like	105..510	CDD:341004	131/408 (32%)