Protein Alignment CG6126 and slc22a2

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_002933908.1
• Gene: slc22a2 / 100487774
• XenbaseID: XB-GENE-965056
• Length: 544
• Species: Xenopus tropicalis
• Alignment Length: 541
• Identity: 171/541 - (31%)
• Similarity: 262/541 - (48%)
• Gaps: 48/541 - (8%)

  Fly     8 EDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSSA 72
            ::|:..:|||..:|...|.|.....:......:.:|.:..||::||...|:...| :...|..:.
 Frog     5 DELLEHIGEFDAFQKQIFILLCFISVVFSPIYVGIVFLGFVPDYRCVSAGIPEPS-NECEWTLNY 68

  Fly    73 ILAAIPLKPNGELES-----CLMFDPSSPGTNTTINC-----------------ERYVYDTTYYK 115
                  ..|||..:|     |..:|..  ..:|::||                 :.:.|:||  .
 Frog    69 ------TGPNGSTDSLYMSQCYQYDVD--WNSTSLNCTNSSLNITSKLPITNCKDGWDYNTT--G 123

  Fly   116 TSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFI 180
            :|...::|.||...|.....|:...:|.|.|.:..|.:||:.|||.....|.|...|.|:.:||.
 Frog   124 SSLVTEFNLVCGDSWKLDFFQSCVNIGFFIGGLISGYIADRFGRKPFLISSILITGIFGILMAFA 188

  Fly   181 PEYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIPD 245
            |.|...:..|::.|.| |.|.::.|::|..|.||...|...||.:||.|..|::|::|...::|.
 Frog   189 PNYPLVVTFRFIQGFV-SKGCWLSGYILVAEFVGLEHRRTVGIVYQAAFTVGLLLLSGVAYVLPH 252

  Fly   246 RQWLQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYYVQKAK 310
            .:|||:...:....||.::|.:.||||||..|.|.|||..|:....:.||..:|    .:::...
 Frog   253 WRWLQMTVTIPYFFFLAYYWCVPESPRWLISQNRKAEAKAIIHTIAKKNGKMVP----DFLESLT 313

  Fly   311 QQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVE 375
            ....|.||......||.|||.:|..||.:...||..::||.|..:..|....|.|...||..|||
 Frog   314 ADEEAGEKQVPSFLDLVRTPQIRKHTLILMYIWFTCAVVYQGSIMHMGSTAENIYFDFFISALVE 378

  Fly   376 FPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQGST----TSTAVVMAGKLLIAGSFAV 436
            |||.|.|:..:||:|||.......:..|:.|::.|:|..|.:    |.:.|...|   |..|:.:
 Frog   379 FPSAILIIVTVDRVGRRYPWLVCCIITGITCLITAFIPHGYSWLIITLSCVSRMG---ITVSYEM 440

  Fly   437 IYNYSAELFPTVVRN-SAMGLGSMCARLSGALTPLITL-LDSFDPKIPAVLFGVVALISGFWVMF 499
            :...:|||:||.:|| ..|...||| .|.|.:||.|.. |.:...::|.::|.|:|.:||..|.|
 Frog   441 VCLVNAELYPTFIRNLGIMVCSSMC-DLGGVITPFIVYRLAAIWQELPLIVFAVLATVSGILVYF 504

  Fly   500 LPETMNQPMPESIEDGENFGK 520
            ||||..:.:||:||:.||..|
 Frog   505 LPETKGRALPETIEEAENLHK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	163/522 (31%)
slc22a2	XP_002933908.1	2A0119	12..516	CDD:273328	164/523 (31%)