Protein Alignment CG6126 and sv2a

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_012825002.1
• Gene: sv2a / 100379721
• XenbaseID: XB-GENE-968429
• Length: 729
• Species: Xenopus tropicalis
• Alignment Length: 680
• Identity: 132/680 - (19%)
• Similarity: 217/680 - (31%)
• Gaps: 262/680 - (38%)

  Fly     1 MAVDYVLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSV 65
            :|..|  |.::.:.|. |::|:..:|:..|:.:..|:.:              |:.|.
 Frog   135 LAQQY--EVILQECGH-GRFQWTLYFVLGLALMADGVEI--------------FVVGF------- 175

  Fly    66 TPWNSSAILAAIPLKPNGELESCLMFDPSSPGTNTTINCERYVYDTTYYKTSRTIDWNFVCDRRW 130
                         :.|:.|.:.||  ..|:.|                                .
 Frog   176 -------------VLPSAEKDMCL--SDSNKG--------------------------------M 193

  Fly   131 MGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARYLLGI 195
            :|.||    .||:..||...||:||::||:.....|.....:.....:|:..|.:|:..|.|.|
 Frog   194 LGLIV----YLGMMVGAFLWGGMADRIGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCRLLSG- 253

  Fly   196 VGSAGAYICGFVLTMELVGPTKRTVCG--ITFQAVF--AGGIMLVAGWGALIPDRQW---LQVIY 253
            ||..|:....|....|.:...||   |  :::..:|  .|||...|...|:||...|   :...|
 Frog   254 VGIGGSIPIVFSYFSEFLAQEKR---GEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFQMGSAY 315

  Fly   254 GLHG-------CLF-----LGHWWWLDESPRWLWMQGRAAEAVDIVAK----GLRINGSGIPVDK 302
            ..|.       |.|     :|....:.||||:....|:..||..::.:    .:|..|....|..
 Frog   316 QFHSWRVFVLVCAFPSVFAIGALTTMPESPRFFLENGKHDEAWMVLKQVHDTNMRAKGHPERVFS 380

  Fly   303 EYYVQKAKQ-QAAAEEKSSAG---------LSDLFR----------TPNLRMKTLNVCLCWFANS 347
            ...::..|| ....|.:|..|         |.:|.:          .|..|..||.:...||..|
 Frog   381 VTQIKTIKQDDELVEIQSDTGALHRRWMIKLLNLSQEVWANFHQCFAPEYRRITLMMMAVWFTMS 445

  Fly   348 LVYYGLSL---------------SAGKLY------------------------------------ 361
            ..||||::               |..|.:
 Frog   446 FSYYGLTVWFPDMIKHLQNIDYASRTKYFHNESVNNFNFNFTLENQVHRKGEYHNDKFIGLKLKS 510

  Fly   362 ----------------------------------------------------------------- 361
                                                                             
 Frog   511 VIFEDSLFTDCYFEDITSSNTFFKNCSFIRTMFYNTDLFDYKFINSKFTNSTFLHSKEGCQLDFS 575

  Fly   362 ---GNPYLILFI--MG-LVEFPSYITIVFVLDRLGRRSITSTLMLGGG--LCCIVAAYIAQGSTT 418
               .|.|:|.|:  :| |...|..|....::|::||     ..||.|.  :.||...::..|::.
 Frog   576 DDINNAYMIYFVSFLGTLAVLPGNIVSALLMDKIGR-----LRMLAGSSVMSCISCFFLFFGNSE 635

  Fly   419 STAVVMA---GKLLIAGSFAVIYNYSAELFPTVVRNSAMG-LGSMCARLSGALTPLITLLDSF-- 477
            |..:.:.   |.:.|| |:..:...:.||:|:..|.:|.| |.::| :|:..|.  |::..||
 Frog   636 SAMIALLCLFGGVSIA-SWNALDVLTVELYPSDKRTTAFGFLNALC-KLAAVLG--ISIFTSFVG 696

  Fly   478 -DPKIPAVLFGVVALISGFWVMFLPETMNQ 506
             ...:|.:|......:..|..:.||||..|
 Frog   697 VAKAVPILLASAALAVGSFLALKLPETRGQ 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	129/666 (19%)
sv2a	XP_012825002.1	synapt_SV2	1..729	CDD:130366	132/680 (19%)