DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mhcl and spring1

DIOPT Version :9

Sequence 1:	NP_732109.2	Gene:	Mhcl / 41955	FlyBaseID:	FBgn0026059	Length:	2194	Species:	Drosophila melanogaster
Sequence 2:	NP_001016016.1	Gene:	spring1 / 548770	XenbaseID:	XB-GENE-5956985	Length:	204	Species:	Xenopus tropicalis

Alignment Length:	143	Identity:	25/143 - (17%)
Similarity:	54/143 - (37%)	Gaps:	33/143 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   639 RSLVETRRDQSLIFMGRSGSGKSTSFKHA--------------LNYLA-----LAAGAYNNFINA 684
            |:|::|.:||::.:..:...|.|:...:.              :.|:.     ||.|..|..:.:
Frog    45 RTLLQTDQDQNIQWKVQFNLGNSSRISNQCRNSVQGKLLITDDMGYICERKELLANGCCNINVAS 109

  Fly   685 EKV--------NALCTILEAFGNTKTCLNSN----ATRMTQLLSLDFDQTGQIASASLQVLLPER 737
            .|:        |..|::.|..  ...||..|    ..|.....::.|....|......::.|.:.
Frog   110 TKLYSCETCLSNGCCSVYEYC--VSCCLQPNKQLLLERFLNRAAVAFQNLFQAVEDHFELCLAKC 172

  Fly   738 QRAGRRLGHEHSF 750
            :.:.:.:.||:::
Frog   173 RTSSQSVQHENTY 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mhcl	NP_732109.2	PDZ_signaling	339..426	CDD:238492
		MYSc	556..1317	CDD:214580	25/143 (17%)
		MYSc_Myo18	575..1305	CDD:276837	25/143 (17%)
		GBP_C	<1540..1750	CDD:303769
		COG1340	1565..1833	CDD:224259
		coiled coil	1723..1734	CDD:293879
spring1	NP_001016016.1	DUF2054	73..194	CDD:370892	18/115 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900