Protein Alignment Mhcl and X11L

DIOPT Version :9

• Sequence 1: NP_732109.2
• Gene: Mhcl / 41955
• FlyBaseID: FBgn0026059
• Length: 2194
• Species: Drosophila melanogaster
• Sequence 2: NP_001285376.1
• Gene: X11L / 252671
• FlyBaseID: FBgn0026313
• Length: 1170
• Species: Drosophila melanogaster
• Alignment Length: 645
• Identity: 131/645 - (20%)
• Similarity: 194/645 - (30%)
• Gaps: 268/645 - (41%)

  Fly    31 SGGPGMGGVTGVTG-----SMSTDELLR-LDEVRRSLKIRGRRKEK-----EKLPS--------- 75
            |.|.|: |||.||.     |.:..|:.. :.|:|.:|:....:.||     |.||:
  Fly   560 SAGSGL-GVTPVTAGGSLPSQAASEIQEAMKEIRSALQRAKTQPEKLKFCDEVLPTDPDSPVWVP 623

  Fly    76 ----------GITADY------------------SADFFA---ALNADANGG----SNGGAVGAA 105
                      |..||.                  ..||||   ..:.:||.|    |||...|.:
  Fly   624 RKGTTISTAQGAAADEEPDTDLETDRLLGQQRHDEQDFFADQSLADNNANEGTDIASNGHLNGTS 688

  Fly   106 DPEQDRGNEEIVASVMTHIESRASNGAGVSVNYSEVTHSLLSGGLKNRFLPPIPPKPPKRGILKG 170
            |  .:..|....:...|:..:....|.|.|                      :.|..|....:.|
  Fly   689 D--NNNPNPMNNSKPQTYSTATIRQGIGTS----------------------LTPNSPDICQIVG 729

  Fly   171 SRSNMTNVHEEISFAGSAGG--------AGGTPEMLLRN---TFQNESLYEGAARGAGSIGSNSS 224
            :.....:..|::.|..|..|        |....:...||   ..:.:.|.||....|..:||.
  Fly   730 TTDISISSPEKLQFTKSPTGSIKSLKDSANSDKKAKSRNKEGLLEPKVLIEGVLFRARYLGST-- 792

  Fly   225 QHGTSFTSVESLRSDGEQTGGQQRAMTLPANARYGAL-PQGNSQGSHL----------------- 271
                      .|..:|:.|...:......|.:|..|| |:|.||.|..
  Fly   793 ----------QLVCEGQPTKSTRMMQAEEAVSRIKALAPEGESQPSTEVDLFISTEKIMVLNTDL 847

  Fly   272 ------HVLTSPSPSAD----------------SLTDTTNSSFATPPFSLSPVGESQGIDRWARV 314
                  |.|.:.|..||                |:.|         |...||:|
  Fly   848 KEIMMDHALRTISYIADIGDLVVLMARRRFVPNSVVD---------PSITSPLG----------- 892

  Fly   315 HAFEDVELPLPPVQLVKLPPPRQLVIRRQKSPR---------------QDFGFSLRKAIC----- 359
                  ::|.|.:. .:..||::.:.:..::|:               |..|.:.:.|..
  Fly   893 ------DVPTPGIG-EEESPPKEPLSKHNRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKA 950

  Fly   360 -----------LDRTESLTS-PIF--RPVIFAE---------PGAGGGATG----------LLP- 390
                       :|..|.|.| .||  ...|||:         |.|.|...|          :||
  Fly   951 NGIENESLAKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPT 1015

  Fly   391 --------------------GDRLIKVNGTPVGELPREIIIEMIRNSGE--AVTVEVQPVAELVE 433
                                ||:||.:||..:..||.......|||:..  ||...|.|...:||
  Fly  1016 VVIANLMSSGAAARCGQLNIGDQLIAINGMSLVGLPLSTCQSYIRNAKNQTAVKFTVVPCPPVVE 1080

  Fly   434 LSKRCMAPSTATVEEIDHSITNG-NCNTLRRSASKRFKRQSRHENGNGGGEEGGAKGVGH 492
            :  :.:.|.  .:.::..|:.|| .|:.||                 ||..|.|...|||
  Fly  1081 V--KILRPK--ALFQLGFSVQNGVICSLLR-----------------GGIAERGGVRVGH 1119

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mhcl	NP_732109.2	PDZ_signaling	339..426	CDD:238492	32/162 (20%)
		MYSc	556..1317	CDD:214580
		MYSc_Myo18	575..1305	CDD:276837
		GBP_C	<1540..1750	CDD:303769
		COG1340	1565..1833	CDD:224259
		coiled coil	1723..1734	CDD:293879
X11L	NP_001285376.1	PTB_X11	775..954	CDD:269919	37/217 (17%)
		PDZ_signaling	988..1065	CDD:238492	17/76 (22%)
		PDZ_signaling	1092..1151	CDD:238492	13/45 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900