Protein Alignment Hel89B and ETL1

DIOPT Version :10

• Sequence 1: NP_732097.2
• Gene: Hel89B / 41943
• FlyBaseID: FBgn0022787
• Length: 1923
• Species: Drosophila melanogaster
• Sequence 2: NP_178318.1
• Gene: ETL1 / 814740
• AraportID: AT2G02090
• Length: 763
• Species: Arabidopsis thaliana
• Alignment Length: 629
• Identity: 188/629 - (29%)
• Similarity: 296/629 - (47%)
• Gaps: 151/629 - (24%)

  Fly  1313 KSDPLQARKTRDREFLDYLFNPKSIPNYKVPVPISVELRCYQQAGINWLWFLNKYNLHG-ILCDD 1376
            ::|...|.|..|.:|                .||   |:.||..|:|:|..|.|..:.| ||.|:
plant   195 QNDIDDACKAEDSDF----------------QPI---LKPYQLVGVNFLLLLYKKGIEGAILADE 240

  Fly  1377 MGLGKTLQTICILAGDHMHRQTANLANL-----PSLVICPPTLTGHWVYEVEKFLDQGSVLRPLH 1436
            ||||||:|.|..|         ..|:.|     |.||:||.::..:|..|:.|:....:||:
plant   241 MGLGKTIQAITYL---------TLLSRLNNDPGPHLVVCPASVLENWERELRKWCPSFTVLQ--- 293

  Fly  1437 YYGFPVGREKLRSDIGT--------KCNLVVASY-------DTVRKDIDFFSGIHFNYCVLDEGH 1486
            |:|  ..|.....::.:        ..|:::..|       :..:.|........::..::||.|
plant   294 YHG--AARAAYSRELNSLSKAGKPPPFNVLLVCYSLFERHSEQQKDDRKVLKRWRWSCVLMDEAH 356

  Fly  1487 IIKNGKTKSSKAIKRL-----KANHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEKQFVQRFSR 1546
            .:|:   |:|...|.|     .||.||:|:|||:||::.|||||.:|::|....||...:::
plant   357 ALKD---KNSYRWKNLMSVARNANQRLMLTGTPLQNDLHELWSLLEFMLPDIFTTENVDLKK--- 415

  Fly  1547 PILSSRDAKSSAKEQEAGVLAMEALHRQVLPFLLRRVKEDVLKDLPPKITQDLLCELSPLQLRLY 1611
             :|::.|.:.        :..|:::   :.||:|||:|.||::.|.|||.:        ::..|.
plant   416 -LLNAEDTEL--------ITRMKSI---LGPFILRRLKSDVMQQLVPKIQR--------VEYVLM 460

  Fly  1612 EDFSNKHLKDCLDKLGDSSSASMVTENLSAKTHIFQAL--RYLQN-------VCNHPKLVLR--Q 1665
            |.......|:.:::...:|.|.:|..:..:...:.:||  |.:.|       :.|||.|:.|  .
plant   461 ERKQEDAYKEAIEEYRAASQARLVKLSSKSLNSLAKALPKRQISNYFTQFRKIANHPLLIRRIYS 525

  Fly  1666 SEELTKVTSQLALSNS-----SLDDI------------------------------EH---SAKL 1692
            .|::.::..:|....:     |||.:                              :|   |||.
plant   526 DEDVIRIARKLHPIGAFGFECSLDRVIEEVKGFNDFRIHQLLFQYGVNDTKGTLSDKHVMLSAKC 590

  Fly  1693 PALKQLLLDCGIGVQTESVSQHRALIFCQLKAMLDIVEQDLLRRHLPSVTYLRLDGSVPASQRQD 1757
            ..|.:||       .:...|.||.|||.|..:||||:|..|   .:..|||.|||||...:.||.
plant   591 RTLAELL-------PSMKKSGHRVLIFSQWTSMLDILEWTL---DVIGVTYRRLDGSTQVTDRQT 645

  Fly  1758 IVNNFNSDPSIDVLLLTTMVGGLGLNLTGADTVIFVEHDWNPMKDLQAMDRAHRIGQKKVVNVYR 1822
            ||:.||:|.||...||:|..||.|||||||||||..:.|:||..|.||.||.|||||.|.|.::|
plant   646 IVDTFNNDKSIFACLLSTRAGGQGLNLTGADTVIIHDMDFNPQIDRQAEDRCHRIGQTKPVTIFR 710

  Fly  1823 LITRNSLEEKIMGLQKFKILTANTVVSA-----ENASL--QTMG 1859
            |:|:::::|.|..:.|.|::....|:.:     :|...  :|||
plant   711 LVTKSTVDENIYEIAKRKLVLDAAVLESGVHVDDNGDTPEKTMG 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hel89B	NP_732097.2	HEAT repeat	5..30	CDD:293787
		HEAT repeat	42..70	CDD:293787
		HEAT repeat	395..420	CDD:293787
		HEAT repeat	433..465	CDD:293787
		HEAT repeat	475..504	CDD:293787
		HEAT repeat	516..540	CDD:293787
		HEAT repeat	560..589	CDD:293787
		DUF3535	654..1138	CDD:463447
		HepA	<1342..1849	CDD:440319	179/581 (31%)
ETL1	NP_178318.1	HepA	<207..737	CDD:440319	180/598 (30%)