Protein Alignment Rbf2 and Rbl2

DIOPT Version :10

• Sequence 1: NP_524372.1
• Gene: Rbf2 / 41941
• FlyBaseID: FBgn0038390
• Length: 783
• Species: Drosophila melanogaster
• Sequence 2: XP_006255261.1
• Gene: Rbl2 / 81758
• RGDID: 3541
• Length: 1136
• Species: Rattus norvegicus
• Alignment Length: 1050
• Identity: 218/1050 - (20%)
• Similarity: 367/1050 - (34%)
• Gaps: 366/1050 - (34%)

  Fly    15 RRFSVSCEQLELEARIQQSALSTYHRLDAVNGLSTSEADAQEWLCCAVYSELQRSKMRDIRESIN 79
            :||...|.:|.::...:..|.|:|.   :::...|.|.:...||.||:|...::| :..:.:...
  Rat    44 QRFEELCSRLNMDEAARAEAWSSYR---SMSESYTLEGNDLHWLACALYVACRKS-VPTVSKGTA 104

  Fly    80 EANDSVAKNCCWNVSLTRLLRSFKMNVSQFLRRMEHWNWLTQNENTFQLEVEELRCRLGITSTLL 144
            |.|         .|||||:||..:.::.:|..:|:.|..:......|:...|.|.....:::.:.
  Rat   105 EGN---------YVSLTRILRCSEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIF 160

  Fly   145 RHYKHIFRSLFVHPGKGADP----GAANHYQ-----ALYEFGWLLFLVIRNELPGFAITNLINGC 200
            :.|:.||:.:|.:| :...|    |.....|     .::.|.|:||:..:...|..: .:|:|..
  Rat   161 KKYEPIFQDIFKYP-QEEQPRQQRGRKQRRQPCTTSEIFHFCWVLFIYAKGNFPMIS-DDLVNSY 223

  Fly   201 QVLVCTMDLLFVNALEVP-RSVVIRREFSGVPKNWDTEDFNPILLNKYSVLEALGELIP--ELPA 262
            .:|:|.:||::.|||:.. |..::...|.||.::....|.:| ..:...|:|.|..|..  .|.|
  Rat   224 HLLLCALDLVYGNALQCSNRKELVNPNFKGVSEDGHPRDSHP-SSDPPCVIEKLCSLHDGLVLEA 287

  Fly   263 KGVVQMKNAFFHKALIMLYMDHSLVGDDTHMREIIKEGMLDINLENLNRKYTNQVADISEMDERV 327
            ||:   |..|:...:..|:....|.|.:.::...::.|....:.:.:|:.|...|.....:|||:
  Rat   288 KGI---KQHFWKPYIRKLFEKKLLRGKEENLTGFLEPGNFAESFKAVNKAYEEYVLATGSLDERI 349

  Fly   328 LLSVQGAIETKGDSPKSPQLAFQTSS-----------------------------------SPSH 357
            .|. :.|.|..|...:....|..|.|                                   ||..
  Rat   350 FLG-EDAEEEVGTLSRCVSAASGTESAERTQMRDILQQHLDKSKTLRVCNPLTGVRYVQENSPCV 413

  Fly   358 RKLS--THDLPASLPLSIIKAFPKKEDADKIVNYLDQTLEEMNRTFTMAVKDFL----------- 409
            ..:|  ||.|..   |..:.|..:...::|    |:|.|...:|..|.|:.|.|
  Rat   414 TPVSTATHSLNR---LHTMLAGLRNAPSEK----LEQILRSCSRDPTRAIADRLREMYEIYSQHF 471

  Fly   410 ---------DAELSGKRFRQARGLYYKYLQKILGPELVQKPQLKIGQLMKQRKLTAALLACCLEL 465
                     ..|::.|.||.|..||||.|:.::..|..:...:.:..:::|.....:|||||||:
  Rat   472 QPDENVSNCAKEMANKHFRFAEMLYYKVLESVIEQEQKRLGDMDLSGVLEQDAFHKSLLACCLEV 536

  Fly   466 ALHVHHKLVEGLRFPFVLHCFSLDAYDFQKILELVVRYDHGFLGRELIKHLDVVEEMCLDSLIFR 530
            ....:..  .| .|||:...|.:..|.|.|::|:.:|.:.| |.||::|||:.:||..||.|.::
  Rat   537 VAFSYKP--PG-NFPFIAEIFDVPHYHFYKVIEVFIRAEDG-LCREVVKHLNQIEEQILDHLAWK 597

  Fly   531 KSSQLWWEL---NQRLPRYKEV------------------------------------------- 549
            ..|.||..:   ..|:|..:||
  Rat   598 TKSPLWDRIRDNENRVPTCEEVTPPHNLERTDEIYIAGSPLTPRRVGEVRTDAGGLGRSVTSPTT 662

  Fly   550 --------------------DAETEDK----------------ENFS------------------ 560
                                |:.:|..                :|.|
  Rat   663 LYDRYSSPTVSTTRRRLFESDSPSEGSTAGRIPPQPLVNAVPVQNVSGETVSVTPVPGQTLVTMA 727

  Fly   561 ------------------------------------------TGS-------------------- 563
                                                      |||
  Rat   728 TATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGGQAQAVTGSIQPLSAQALAGSLSSQQVTG 792

  Fly   564 ----------------------------------------SICLRKFYGLANRRLLLLCKSLCLV 588
                                                    |:..||.|.||..||..||..|.:.
  Rat   793 TTLQVPGPVAIQQISPGGQQQNQGQPLTSSSIRPRKTSSLSLFFRKVYYLAGVRLRDLCTKLDIS 857

  Fly   589 DSF-PQIWHLAEHSFTLESSRLLRNRHLDQLLLCAIHLHVRLEKLHLTFSMIIQHYRRQPHFRRS 652
            |.. .:||...|.|. ::...|:.:|||||||:|||::..::.|...:|..|::.||.||..|..
  Rat   858 DELRKKIWTCFEFSI-VQCPELMMDRHLDQLLMCAIYVMAKVTKEDKSFQNIMRCYRTQPQARSQ 921

  Fly   653 AYREVSLGNGQTADIITFYNSVYVQSMGNYGRHLECAQTRKSLEESQSNVGILTETTSNELS--- 714
            .||.|.:...:.                |.|   .|        |::|:....||..::..|
  Rat   922 VYRSVLIKGKRR----------------NSG---SC--------ENRSHQNSPTELNTDRASRDS 959

  Fly   715 ---MRANISISSPPPPRVCQSGSCSSHPPSSPAASPLSLQSSPNVKRAASSNDLMREIKRPNILR 776
               ||:|.::..|.|         ||.||:.              .|...:|..:.|.:|.::::
  Rat   960 SPVMRSNSTLPVPQP---------SSAPPTP--------------TRLTGANSDIEEEERGDLIQ 1001

  Fly   777 ------RRQL 780
                  |:|:
  Rat  1002 FYNNIYRKQI 1011

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbf2	NP_524372.1	DUF3452	83..213	CDD:463402	32/138 (23%)
		RB_A	<384..536	CDD:460364	51/171 (30%)
		RB_B	<593..679	CDD:460363	26/85 (31%)
Rbl2	XP_006255261.1	CYCLIN_SF	41..131	CDD:410207	26/99 (26%)
		DUF3452	101..236	CDD:463402	34/145 (23%)
		RB_A	414..606	CDD:460364	59/202 (29%)
		SP1-4_N	<696..>834	CDD:425404	5/137 (4%)
		CYCLIN_RBL2	831..1018	CDD:410309	61/231 (26%)