Protein Alignment Rbf2 and rbl1

DIOPT Version :9

• Sequence 1: NP_524372.1
• Gene: Rbf2 / 41941
• FlyBaseID: FBgn0038390
• Length: 783
• Species: Drosophila melanogaster
• Sequence 2: NP_001124082.1
• Gene: rbl1 / 795522
• ZFINID: ZDB-GENE-030131-8179
• Length: 1058
• Species: Danio rerio
• Alignment Length: 1053
• Identity: 225/1053 - (21%)
• Similarity: 375/1053 - (35%)
• Gaps: 332/1053 - (31%)

  Fly     2 ETCEVEGEAETLVRRFSVSCEQLELEARIQQSALSTYHRLDAVNGLSTSEADAQEWLCCAVYSEL 66
            :|..|.....::...|...|::|.::......||..:.   ::....|.|.|...||.|::|:..
Zfish     7 DTESVRSADGSIRSNFEALCQELNMDEETAAEALQNFR---SIWNTYTLEGDVMHWLACSLYAAC 68

  Fly    67 QRSKMRDIRESINEANDSVAKNCCWNVSLTRLLRSFKMNVSQFLRRMEHWNWLTQNENTFQLEVE 131
            ::|.:..:...:.|.|       |  |||||:|||.|:::.||..:|:.|:.:......|:..:.
Zfish    69 RKSSIPTVGRGVMEGN-------C--VSLTRILRSAKLSLIQFFSKMKKWSDMANLCQDFRSRIG 124

  Fly   132 ELRCRLGITSTLLRHYKHIFRSLFVHPGKGADPGAAN---------HYQALYEFGWLLFLVIRNE 187
            .|.....:::.:.|.::.||..:|.:| :...|....         |...:::|.|.||:..:..
Zfish   125 RLERNFEVSTVIFRKFEPIFLDMFQNP-QSEPPRMPRSRKHRRLPCHISDVFKFCWTLFVYTKGN 188

  Fly   188 LPGFAITNLINGCQVLVCTMDLLFVNALEVP-RSVVIRREFSGVPKNWDTEDFN--PILLNKYSV 249
            ..... .:|:|...:|:|.:||:|.|||... |..:|.:.|.|:||  |||:..  |.:::|  :
Zfish   189 FHMIG-DDLVNSYHLLLCCLDLVFCNALMCSNRKDLINQNFRGLPK--DTENLKEMPCVIDK--L 248

  Fly   250 LEALGELIPELPAKGVVQMKNAFFHKALIMLYMDHSLVGDDTHMREIIKEGMLDINLENLNRKYT 314
            .|....|:.|  |||:   |..:|...:..|:....|.||...:.|::.......|.:.:||.|.
Zfish   249 CELHDGLVVE--AKGI---KEHYFKPYIKTLFEKRMLKGDVETLTELLDTPNFQDNNKAINRDYE 308

  Fly   315 NQVADISEMDERVLLSVQG--AIETKGDSPKSPQLAFQTSSSPSHRKLSTH-----DLPASLPLS 372
            ..|..:.:.||||.|....  .|.|...||..|.....::.......|..|     .|..|.||:
Zfish   309 EFVLTVGDFDERVFLGADADEEIGTPRKSPAEPPSGHLSARMQVENNLQQHFEKTRSLAPSTPLT 373

  Fly   373 IIKAFPKKE----------------------------DA-------------DKIVNYLDQTLEE 396
            ..:...:||                            ||             :.|:|.:....|:
Zfish   374 GRRYLKEKEVLVTPVSSATQSVSRLQSMVSGLRNAPSDALLQIFNSCSRNPTESILNRVKTLGEK 438

  Fly   397 MNRTFTMAVKDFLDA--ELSGKRFRQARGLYYKYLQKILGPELVQKPQLKIGQLMKQRKLTAALL 459
            ..:.:|....|...|  :.:.||.:.|..||:|.|:.::..|:.:........|::|..|..:||
Zfish   439 FKQAYTNPTDDLPGAHMDFAEKRLKLAEILYFKILENVMTQEMKRLQGKDWAVLLEQEVLHCSLL 503

  Fly   460 ACCLELALHVHHKLVEGLRFPFVLHCFSLDAYDFQKILELVVRYDHGFLGRELIKHLDVVEEMCL 524
            |||||:.|..:.   ....||::|..|.:..:.|.|::|:.:|.:.| |.|:::|||:.:||..|
Zfish   504 ACCLEVVLFSYS---SQRTFPWILEIFQIPPFYFYKVIEVFIRSEEG-LSRDMVKHLNSIEEQVL 564

  Fly   525 DSLIFRKSSQLWWELNQ---RLPRYKEVDAETEDKENFSTGS----------------------- 563
            :|..:.:.|.||..||:   ::|..:||:..:    ||.||:
Zfish   565 ESRAWTRDSALWNALNKDNNKVPTVEEVNFPS----NFDTGNNAGGPTHLPLVALSPIIHPRLRE 625

  Fly   564 ----------------------------------------------------------------- 563
                                                                             
Zfish   626 VRTGLGSSARKDVPQSPISLHDRYSSPAAGSAKRRLFGDDAPPQSPVKRISVTPIKIIPSGMENQ 690

  Fly   564 ----------------------------------------------------------------- 563
                                                                             
Zfish   691 TTTTTVLSMATGNGQQLTIPLPVVKNEAGGITVIQLQASDMNPLTAQVLLTASPSRPALAAPAIS 755

  Fly   564 -----------------SICLRKFYGLANRRLLLLCKSLCLVDSF-PQIWHLAEHSFTLESSRLL 610
                             ::..||.|.||:.||..||..|.:.... .:||...|||. |..:.|:
Zfish   756 SDSQPPPANKPRRTGSLALFFRKVYHLASVRLRDLCLKLDISSELRGKIWTCFEHSL-LHCTDLM 819

  Fly   611 RNRHLDQLLLCAIHLHVRLEKLHLTFSMIIQHYRRQPHFRRSAYREVSL---------------- 659
            ::||||||||||:::..|:.|...||..|::.||.||......||.|.:
Zfish   820 KDRHLDQLLLCAVYIISRITKEEHTFQDIMKCYRTQPQANSHVYRSVLIKRRPKVQQADENMEVD 884

  Fly   660 -------------GNGQT---------------ADIITFYNSVYVQSMGNYGRHLECAQTRKSLE 696
                         .|.:|               .|:|.|||::||..|.::......:.....:|
Zfish   885 PPADQSNERTDQAANERTDQADRTQTVFESEERGDLIQFYNNIYVSKMRSFAFKYALSTLDNRME 949

  Fly   697 ESQSNVGILTETTSNELSMRANISISSPPPPRVCQSGS--CSSHPPSS----PAASPLSLQSSPN 755
                         :..||...::...:..|.||.|..|  .|.|..||    ..|.......||:
Zfish   950 -------------APPLSPFPSVRSHTLSPRRVSQKHSIFVSPHKNSSSLTPSTAYTYRFTGSPS 1001

  Fly   756 VKRAASSNDLMRE 768
             |..:..|.::|:
Zfish  1002 -KELSDINQMIRQ 1013

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbf2	NP_524372.1	DUF3452	83..210	CDD:288762	32/135 (24%)
		RB_A	380..536	CDD:280101	48/198 (24%)
		CYCLIN	564..679	CDD:294043	48/159 (30%)
rbl1	NP_001124082.1	DUF3452	79..210	CDD:288762	34/141 (24%)
		RB_A	386..579	CDD:280101	48/196 (24%)
		RB_B	771..932	CDD:280100	48/161 (30%)
		Rb_C	951..>1041	CDD:286075	17/64 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580909
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1010
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46367
OrthoDB	1	1.010	-	-		D113612at2759
OrthoFinder	1	1.000	-	-		FOG0002362
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.820