Protein Alignment Rbf2 and rbl1

DIOPT Version :10

• Sequence 1: NP_524372.1
• Gene: Rbf2 / 41941
• FlyBaseID: FBgn0038390
• Length: 783
• Species: Drosophila melanogaster
• Sequence 2: NP_001124082.1
• Gene: rbl1 / 795522
• ZFINID: ZDB-GENE-030131-8179
• Length: 1058
• Species: Danio rerio
• Alignment Length: 1053
• Identity: 225/1053 - (21%)
• Similarity: 375/1053 - (35%)
• Gaps: 332/1053 - (31%)

  Fly     2 ETCEVEGEAETLVRRFSVSCEQLELEARIQQSALSTYHRLDAVNGLSTSEADAQEWLCCAVYSEL 66
            :|..|.....::...|...|::|.::......||..:.   ::....|.|.|...||.|::|:..
Zfish     7 DTESVRSADGSIRSNFEALCQELNMDEETAAEALQNFR---SIWNTYTLEGDVMHWLACSLYAAC 68

  Fly    67 QRSKMRDIRESINEANDSVAKNCCWNVSLTRLLRSFKMNVSQFLRRMEHWNWLTQNENTFQLEVE 131
            ::|.:..:...:.|.|       |  |||||:|||.|:::.||..:|:.|:.:......|:..:.
Zfish    69 RKSSIPTVGRGVMEGN-------C--VSLTRILRSAKLSLIQFFSKMKKWSDMANLCQDFRSRIG 124

  Fly   132 ELRCRLGITSTLLRHYKHIFRSLFVHPGKGADPGAAN---------HYQALYEFGWLLFLVIRNE 187
            .|.....:::.:.|.::.||..:|.:| :...|....         |...:::|.|.||:..:..
Zfish   125 RLERNFEVSTVIFRKFEPIFLDMFQNP-QSEPPRMPRSRKHRRLPCHISDVFKFCWTLFVYTKGN 188

  Fly   188 LPGFAITNLINGCQVLVCTMDLLFVNALEVP-RSVVIRREFSGVPKNWDTEDFN--PILLNKYSV 249
            ..... .:|:|...:|:|.:||:|.|||... |..:|.:.|.|:||  |||:..  |.:::|  :
Zfish   189 FHMIG-DDLVNSYHLLLCCLDLVFCNALMCSNRKDLINQNFRGLPK--DTENLKEMPCVIDK--L 248

  Fly   250 LEALGELIPELPAKGVVQMKNAFFHKALIMLYMDHSLVGDDTHMREIIKEGMLDINLENLNRKYT 314
            .|....|:.|  |||:   |..:|...:..|:....|.||...:.|::.......|.:.:||.|.
Zfish   249 CELHDGLVVE--AKGI---KEHYFKPYIKTLFEKRMLKGDVETLTELLDTPNFQDNNKAINRDYE 308

  Fly   315 NQVADISEMDERVLLSVQG--AIETKGDSPKSPQLAFQTSSSPSHRKLSTH-----DLPASLPLS 372
            ..|..:.:.||||.|....  .|.|...||..|.....::.......|..|     .|..|.||:
Zfish   309 EFVLTVGDFDERVFLGADADEEIGTPRKSPAEPPSGHLSARMQVENNLQQHFEKTRSLAPSTPLT 373

  Fly   373 IIKAFPKKE----------------------------DA-------------DKIVNYLDQTLEE 396
            ..:...:||                            ||             :.|:|.:....|:
Zfish   374 GRRYLKEKEVLVTPVSSATQSVSRLQSMVSGLRNAPSDALLQIFNSCSRNPTESILNRVKTLGEK 438

  Fly   397 MNRTFTMAVKDFLDA--ELSGKRFRQARGLYYKYLQKILGPELVQKPQLKIGQLMKQRKLTAALL 459
            ..:.:|....|...|  :.:.||.:.|..||:|.|:.::..|:.:........|::|..|..:||
Zfish   439 FKQAYTNPTDDLPGAHMDFAEKRLKLAEILYFKILENVMTQEMKRLQGKDWAVLLEQEVLHCSLL 503

  Fly   460 ACCLELALHVHHKLVEGLRFPFVLHCFSLDAYDFQKILELVVRYDHGFLGRELIKHLDVVEEMCL 524
            |||||:.|..:.   ....||::|..|.:..:.|.|::|:.:|.:.| |.|:::|||:.:||..|
Zfish   504 ACCLEVVLFSYS---SQRTFPWILEIFQIPPFYFYKVIEVFIRSEEG-LSRDMVKHLNSIEEQVL 564

  Fly   525 DSLIFRKSSQLWWELNQ---RLPRYKEVDAETEDKENFSTGS----------------------- 563
            :|..:.:.|.||..||:   ::|..:||:..:    ||.||:
Zfish   565 ESRAWTRDSALWNALNKDNNKVPTVEEVNFPS----NFDTGNNAGGPTHLPLVALSPIIHPRLRE 625

  Fly   564 ----------------------------------------------------------------- 563
                                                                             
Zfish   626 VRTGLGSSARKDVPQSPISLHDRYSSPAAGSAKRRLFGDDAPPQSPVKRISVTPIKIIPSGMENQ 690

  Fly   564 ----------------------------------------------------------------- 563
                                                                             
Zfish   691 TTTTTVLSMATGNGQQLTIPLPVVKNEAGGITVIQLQASDMNPLTAQVLLTASPSRPALAAPAIS 755

  Fly   564 -----------------SICLRKFYGLANRRLLLLCKSLCLVDSF-PQIWHLAEHSFTLESSRLL 610
                             ::..||.|.||:.||..||..|.:.... .:||...|||. |..:.|:
Zfish   756 SDSQPPPANKPRRTGSLALFFRKVYHLASVRLRDLCLKLDISSELRGKIWTCFEHSL-LHCTDLM 819

  Fly   611 RNRHLDQLLLCAIHLHVRLEKLHLTFSMIIQHYRRQPHFRRSAYREVSL---------------- 659
            ::||||||||||:::..|:.|...||..|::.||.||......||.|.:
Zfish   820 KDRHLDQLLLCAVYIISRITKEEHTFQDIMKCYRTQPQANSHVYRSVLIKRRPKVQQADENMEVD 884

  Fly   660 -------------GNGQT---------------ADIITFYNSVYVQSMGNYGRHLECAQTRKSLE 696
                         .|.:|               .|:|.|||::||..|.::......:.....:|
Zfish   885 PPADQSNERTDQAANERTDQADRTQTVFESEERGDLIQFYNNIYVSKMRSFAFKYALSTLDNRME 949

  Fly   697 ESQSNVGILTETTSNELSMRANISISSPPPPRVCQSGS--CSSHPPSS----PAASPLSLQSSPN 755
                         :..||...::...:..|.||.|..|  .|.|..||    ..|.......||:
Zfish   950 -------------APPLSPFPSVRSHTLSPRRVSQKHSIFVSPHKNSSSLTPSTAYTYRFTGSPS 1001

  Fly   756 VKRAASSNDLMRE 768
             |..:..|.::|:
Zfish  1002 -KELSDINQMIRQ 1013

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbf2	NP_524372.1	DUF3452	83..213	CDD:463402	34/138 (25%)
		RB_A	<384..536	CDD:460364	44/153 (29%)
		RB_B	<593..679	CDD:460363	38/129 (29%)
rbl1	NP_001124082.1	DUF3452	79..213	CDD:463402	36/144 (25%)
		RB_A	386..579	CDD:460364	48/196 (24%)
		CYCLIN_RBL1	765..939	CDD:410308	49/174 (28%)