DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5213 and Hnrnpr

DIOPT Version :9

Sequence 1:	NP_650473.1	Gene:	CG5213 / 41892	FlyBaseID:	FBgn0038345	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_006539285.1	Gene:	Hnrnpr / 74326	MGIID:	1891692	Length:	635	Species:	Mus musculus

Alignment Length:	322	Identity:	69/322 - (21%)
Similarity:	124/322 - (38%)	Gaps:	96/322 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AGIRGMFQ-TGRPVD----------PPPP------LPNLRMKTNLILNYLPQDMTESELHRLFSK 63
            |.|:.:.: ||..:|          |||.      .|.:  .|.:.:..:|:|:.|.||..||.|
Mouse   125 AKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGI--GTEVFVGKIPRDLYEDELVPLFEK 187

  Fly    64 FGEIRKAKIIRHRRTGISCCYGFVDYVSERQAAAAVNGMDGYETR-GKRLKVAFARPSEYESTSS 127
            .|.|...:::....:|.:..|.|:.:..:..|..||...|.||.| ||.|.|..:      ..::
Mouse   188 AGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCIS------VANN 246

  Fly   128 SLYVGNLPTYMDEKKVRELFA-----TYGNIVDVNLLRHKFNN--RSRGVAFLQFELVRDAEVAK 185
            .|:||::|....::.:.|.|:     |.| :||| :|.|:.::  ::||..||::|..:.|..|:
Mouse   247 RLFVGSIPKNKTKENILEEFSKVTGLTEG-LVDV-ILYHQPDDKKKNRGFCFLEYEDHKSAAQAR 309

  Fly   186 YGMDRYMIEGASRPLTVK----------------------------------------------- 203
            ..:....::.....:||:
Mouse   310 RRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVK 374

  Fly   204 ------FVEREKKGSS----STSSGSQYKDKR----KSSPPPYKRRERTNDHHVSKRSRDSD 251
                  ||..|.:|::    ...:|.:.:.:.    .:.||..||:||......|:.:...|
Mouse   375 KLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYED 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5213	NP_650473.1	RRM1_Hu_like	41..117	CDD:240821	25/76 (33%)
CG5213	NP_650473.1	RRM	128..202	CDD:214636	20/80 (25%)
Hnrnpr	XP_006539285.1	hnRNP_Q_AcD	37..106	CDD:375786
Hnrnpr	XP_006539285.1	hnRNP-R-Q	106..630	CDD:273732	69/322 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910