DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5213 and Pabpc6

DIOPT Version :9

Sequence 1:	NP_650473.1	Gene:	CG5213 / 41892	FlyBaseID:	FBgn0038345	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001157308.1	Gene:	Pabpc6 / 67543	MGIID:	1914793	Length:	643	Species:	Mus musculus

Alignment Length:	222	Identity:	55/222 - (24%)
Similarity:	96/222 - (43%)	Gaps:	38/222 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 TNLILNYLPQDMTESELHRLFSKFGEIRKAKIIRHRRTGISCCYGFVDYVSERQAAAAVNGMDGY 105
            ||:.:..|.:||.:..|..||.:||.....|::.. .:|.|..:|||.:.....|..||..|:|.
Mouse   191 TNVYIKNLGEDMDDERLQDLFGRFGPALSVKVMTD-ESGKSKGFGFVSFERHEDARKAVEEMNGK 254

  Fly   106 ETRGKRLKVAFARPSEYEST----------------------------SSSLYVGNLPTYMDEKK 142
            :..||::.|..|:......|                            ..:|||.||...:|:::
Mouse   255 DLNGKQIYVGRAQKKVERQTELKHKFGQMKQDKHKIERVPQDRSVRCKGVNLYVKNLDDGIDDER 319

  Fly   143 VRELFATYGNIVDVNLLRHKFNNRSRGVAFLQFELVRDAEVAKYGMDRYMIEGASRPLTVKFVER 207
            :|:.|:.:|.|....:...  ..||:|..|:.|....:|..|...|:..::  |::||.|...:|
Mouse   320 LRKEFSPFGTITSAKVTME--GGRSKGFGFVCFSSPEEATKAVTEMNGKIV--ATKPLYVALAQR 380

  Fly   208 EKKGSSSTSSGSQYKDKRKSS---PPP 231
            :::..:..|  :||..:..|:   |.|
Mouse   381 KEERQAHLS--NQYMQRMASTSAGPNP 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5213	NP_650473.1	RRM1_Hu_like	41..117	CDD:240821	24/75 (32%)
CG5213	NP_650473.1	RRM	128..202	CDD:214636	21/73 (29%)
Pabpc6	NP_001157308.1	PABP-1234	11..622	CDD:130689	55/222 (25%)
		RRM1_I_PABPs	12..91	CDD:240824
		RRM2_I_PABPs	97..172	CDD:240825
		RRM3_I_PABPs	190..269	CDD:240826	25/78 (32%)
		RRM4_I_PABPs	303..380	CDD:240827	22/80 (28%)
		PABP	554..621	CDD:279051
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910