DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5213 and ELAVL4

DIOPT Version :9

Sequence 1:	NP_650473.1	Gene:	CG5213 / 41892	FlyBaseID:	FBgn0038345	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_011539191.1	Gene:	ELAVL4 / 1996	HGNCID:	3315	Length:	416	Species:	Homo sapiens

Alignment Length:	226	Identity:	82/226 - (36%)
Similarity:	121/226 - (53%)	Gaps:	16/226 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 QTGRPVDPPPPLPNLRMKTNLILNYLPQDMTESELHRLFSKFGEIRKAKIIRHRRTGISCCYGFV 87
            |||...|.        .|||||:|||||:||:.|...||...|||...|::|.:.||.|..||||
Human    72 QTGATTDD--------SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFV 128

  Fly    88 DYVSERQAAAAVNGMDGYETRGKRLKVAFARPSEYESTSSSLYVGNLPTYMDEKKVRELFATYGN 152
            :|:..:.|..|:|.::|...:.|.:||::||||......::|||..||..|.:|::.:||:.||.
Human   129 NYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGR 193

  Fly   153 IVDVNLLRHKFNNRSRGVAFLQFELVRDAEVAKYGMDRYMIEGASRPLTVKFVEREKKGSSSTSS 217
            |:...:|..:....||||.|::|:...:||.|..|::.....||:.|:||||.....:.||....
Human   194 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALL 258

  Fly   218 GSQYKDKRKSSPPPYKRRERTNDHHVSKRSR 248
            ...|:...:..|.|.        ||.::|.|
Human   259 SQLYQSPNRRYPGPL--------HHQAQRFR 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5213	NP_650473.1	RRM1_Hu_like	41..117	CDD:240821	34/75 (45%)
CG5213	NP_650473.1	RRM	128..202	CDD:214636	26/73 (36%)
ELAVL4	XP_011539191.1	ELAV_HUD_SF	79..415	CDD:273741	78/219 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000313
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910