Protein Alignment obe and Mtr4

DIOPT Version :10

• Sequence 1: NP_650472.2
• Gene: obe / 41891
• FlyBaseID: FBgn0038344
• Length: 2183
• Species: Drosophila melanogaster
• Sequence 2: NP_524929.1
• Gene: Mtr4 / 48782
• FlyBaseID: FBgn0001986
• Length: 1055
• Species: Drosophila melanogaster
• Alignment Length: 876
• Identity: 216/876 - (24%)
• Similarity: 356/876 - (40%)
• Gaps: 239/876 - (27%)

  Fly  1294 PLSFQHLVLPEHHPPLTELLPLRPLPVSCLKNVVYESLYKFTHFNPIQTQIFHCLYHTDN--NVL 1356
            |.|..|.|..  ||. .|.:||:|.      :.|....|.|. .:|.|.|...|:   ||  :||
  Fly   119 PKSCTHEVAA--HPD-QEYIPLKPF------SGVPAKEYPFV-LDPFQRQAILCI---DNSQSVL 170

  Fly  1357 LGAPTGSGKTIVAEIAIFRALNQNPKCKVVYIAPLKALVKERIADWEQRFQRSSLGLKVVELTGD 1421
            :.|.|.:|||:|||.||.::|  ..|.:|:|..|:|||..::..::...|:  .:||    :|||
  Fly   171 VSAHTSAGKTVVAEYAIAKSL--AAKQRVIYTTPIKALSNQKFREFTDEFK--DVGL----VTGD 227

  Fly  1422 VTPDIQAIRESQLIVTTPEKWDGISRS--WQTREYVQHVSLIVIDEIHLL-GEDRGPVIE--VIV 1481
            ||.:..|   |.||:||.     |.|:  ::..|.::.|..:|.||||.: .::||.|.|  :|:
  Fly   228 VTINPSA---SCLIMTTE-----ILRNMLYRGSEIMREVGWVVFDEIHYMRDKERGVVWEETLIL 284

  Fly  1482 SRTNFISSHTGRAIRIVGLSTALANAQDLANWL-GINKMGLYNFKPSVRPVPLQVHINGFP---- 1541
            ...|         :|.|.||..:.||:..|.|: .::|...:......||.|||.:|  ||
  Fly   285 LPDN---------VRYVFLSATIPNARQFAEWVCHLHKQPCHVVYTDYRPTPLQHYI--FPAGGD 338

  Fly  1542 GKH-------------YCPRMATM------------------------NRPTFQAI-----RTYS 1564
            |.|             :...||.:                        ....|:.:     |.::
  Fly   339 GIHLIVDEKGQFKEDNFTTAMAVLANAGEAGKGDQKGRHGGIKGTNAGQTNIFKIVKMIMERNFA 403

  Fly  1565 PCEPTIVFVSSRRQTRLTALDLITFVAGESNPKQFLHIPEDEI-----ELILQNIRE----QNLK 1620
               |.|:|..|::...:.|:.:........:.|:.:    ||:     :::.:..|.    :|:.
  Fly   404 ---PVIIFSFSKKDCEIYAMQMAKLDFNTPDEKKLV----DEVFNNAMDVLTEEDRRLPQVENVL 461

  Fly  1621 FCLAFGIGLHHAGLQEQDRKCVEELFLNRKIQILVATATLAWGVNLPAHLVVIKGTEYFDGKVKK 1685
            ..|..|||:||.||....::.:|.||....|:.|.||.|.|.|:|:||..|:......||||..:
  Fly   462 PLLRRGIGIHHGGLLPILKETIEILFGEGLIKALFATETFAMGLNMPARTVLFTAPRKFDGKKFR 526

  Fly  1686 YVDMPITDVLQMMGRAGRPQFDNEGVAVVLVHDEKKNFYKKFLYDPFPVESSLLGVLPEHINAEI 1750
            ::..  .:.:||.|||||...|::|: |:|:.|||                    |.|. :..:|
  Fly   527 WISS--GEYIQMAGRAGRRGLDDKGI-VILMIDEK--------------------VSPA-VGRDI 567

  Fly  1751 VAGTVQSKQAALDYLTWTYFFRRLLR----NP------SYYQLQDIEPENVNNFMSNLVERVVYE 1805
            |.|......:|. :||:.... .|||    ||      |:||.|:   :.....:.:.||:...|
  Fly   568 VQGKADPINSAF-HLTYNMVL-NLLRVEEINPEYMLERSFYQFQN---QAALPGLHDQVEQKTLE 627

  Fly  1806 LSAAACLVERDGCLIPTFLGRISSYYYLSYRTMKH-------------FLEDLQPGMNTKKVLLA 1857
            |:......|.:          |:||:::..:..:|             .|..||||    :::..
  Fly   628 LNKLTIKDEHN----------IASYHHIRSQLDQHGKQFRQWITKPQYLLPFLQPG----RLVKV 678

  Fly  1858 IADSYEFDQLPV----RHNEDKHNEEMAEVSRFRPPSSSWDSSYTKTFLLLQAHFARQSLPNSDY 1918
            .|.|.|:|...|    :.::.:.|...||      ||.:.|       :||  |.:..:....
  Fly   679 AAGSQEYDWGIVLNFKKQDQSRKNPLKAE------PSVTID-------VLL--HVSEAAAKTG-- 726

  Fly  1919 LTDTKSALDNATRVMQAMVDYTAERGWLSTTLVVQQLMQSVIQARWFDGSEFLTLPGVNEDNLDA 1983
              ||:....|             |||.:....|...|:..:...|.:..::..     :.||..|
  Fly   727 --DTEPCKPN-------------ERGCMEVVPVAHTLITQISSIRVYFPNDLR-----SADNRRA 771

  Fly  1984 FLNIPHDDYDYLTL--PVLKELCKQEYEVLAKPLRD----------AFEEH------EIEKMYKV 2030
            .|....:......|  |||..:  .:..:..:..||          ..|||      |:|::::.
  Fly   772 VLKTIQEAKKRFPLGPPVLNPI--DDMNIKDREFRDIVNTISQFEKRLEEHPLHKSPELERIHRR 834

  Fly  2031 IQDLPEIAIQIFVEGRHMENEYAKRPLSLSD 2061
            .||  ::.:|..::....|.:.|:..|.:.:
  Fly   835 YQD--KVTLQKQLQDLKAELKAARSLLQMDE 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
obe	NP_650472.2	Helicase_PWI	<247..>284	CDD:436309
		BRR2	485..1025	CDD:440817
		DEXHc_ASCC3_1	486..683	CDD:350778
		SEC63	985..1298	CDD:214744	2/3 (67%)
		BRR2	1334..1859	CDD:440817	160/610 (26%)
		DEXHc_ASCC3_2	1336..1525	CDD:350780	64/196 (33%)
		SEC63	1818..2176	CDD:214744	53/279 (19%)
Mtr4	NP_524929.1	Dob10	145..1048	CDD:443638	205/841 (24%)