Protein Alignment obe and PolQ

DIOPT Version :10

• Sequence 1: NP_650472.2
• Gene: obe / 41891
• FlyBaseID: FBgn0038344
• Length: 2183
• Species: Drosophila melanogaster
• Sequence 2: NP_524333.1
• Gene: PolQ / 41571
• FlyBaseID: FBgn0002905
• Length: 2059
• Species: Drosophila melanogaster
• Alignment Length: 1091
• Identity: 219/1091 - (20%)
• Similarity: 394/1091 - (36%)
• Gaps: 316/1091 - (28%)

  Fly  1043 ELDELKNAYCKIKPYGGS---ENVHGKVNILIQTYLSNGYVKSFSLSSDMSY-----ITTNIGRI 1099
            :.|:.:||    :|..|:   ::...:||..||...|..:...||...:.::     ...|:.::
  Fly    22 QADDKENA----QPGNGNIQVQSAGNEVNSEIQEINSEFFRDEFSYEVNQAHKPAEQSVVNVSQV 82

  Fly  1100 SRALFSIVLRQNNAVLSGNML---QLC--KMFERRQWDFDCHLKQFPTINAETIDKLERRGLSVY 1159
            .:.: ::|..|::...|.:..   |:|  ..||......|..|.| |.::
  Fly    83 QQHM-AVVSNQDSEDQSRSSALNDQICTQSSFEGEDAGADAVLDQ-PNLD--------------- 130

  Fly  1160 RLRDMEHRELKEWLRSNTYADLVIRSAHELPLLEVEASLQPITRTVLRIKVDIWPSFTWNDRVHG 1224
                           .|::.         .|..:.|||.|        :|.||..|.:    |..
  Fly   131 ---------------ENSFL---------CPAQDEEASEQ--------LKEDILHSHS----VLA 159

  Fly  1225 KTCQSFWLWIEDPESNYIYHSELFQVTR--------KLVMSGQSQQLVMTIPLKEPLPPQYYIRV 1281
            |  |.|             :.|:.|||:        :|.:|..|.::...:|.:..:|.......
  Fly   160 K--QEF-------------YQEISQVTQNLSSMSPNQLRVSPNSSRIREAMPERPAMPLDLNTLR 209

  Fly  1282 SSDNWLGSTTCIPLSFQHLVLPEHHPPLTELLPLRPLPVSCLK--NVVYESLYKFTHFNPIQTQI 1344
            |...|     .:|:|.|    .|:..  ..::.:....|.||.  .:::|
  Fly   210 SISAW-----NLPMSIQ----AEYKK--KGVVDMFDWQVECLSKPRLLFE--------------- 248

  Fly  1345 FHCLYHTDNNVLLGAPTGSGKTIVAEIAIFRALNQNPKCKVVYIAPLKALVKERIADWEQRFQRS 1409
             ||      |::..|||.:|||:|:||.:.:.:.:..| ||:.|.|..::|:|::      |...
  Fly   249 -HC------NLVYSAPTSAGKTLVSEILMLKTVLERGK-KVLLILPFISVVREKM------FYMQ 299

  Fly  1410 SL----GLKVVELTGDVTPDIQAIRESQLIVTTPEKWDGISRSWQTREYVQHVSLIVIDEIHLLG 1470
            .|    |.:|....|..||. .......:.:.|.||.:.|......:..::.:.::|:||:||:.
  Fly   300 DLLTPAGYRVEGFYGGYTPP-GGFESLHVAICTIEKANSIVNKLMEQGKLETIGMVVVDEVHLIS 363

  Fly  1471 E-DRGPVIEVIVSRTNFISSHTGRAIRIVGLSTALANAQDLANWLGINKMGLYNFKP-------- 1526
            : .||.::|:::::..::|...|..|:::.:|..|.|.|.|.:||.. ::.:.|::|
  Fly   364 DKGRGYILELLLAKILYMSRRNGLQIQVITMSATLENVQLLQSWLDA-ELYITNYRPVALKEMIK 427

  Fly  1527 -----------SVRPVPLQ-VHINGF-------------------------PGKHYCPRMATMNR 1554
                       .||.|..| |.:.|.                         |.|.:|..:|..
  Fly   428 VGTVIYDHRLKLVRDVAKQKVLLKGLENDSDDVALLCIETLLEGCSVIVFCPSKDWCENLAVQ-- 490

  Fly  1555 PTFQAIRTYSPCEPTIVFVSSRRQTRLTALDLITFVAGESNPKQFLHIPED--EIELILQNIREQ 1617
             ...||......|..:   ..|.:|.|             ||:....:.:.  :|...|..:..:
  Fly   491 -LATAIHVQIKSETVL---GQRLRTNL-------------NPRAIAEVKQQLRDIPTGLDGVMSK 538

  Fly  1618 NLKFCLAFGIGLHHAGLQEQDRKCVEELFLNRKIQILVATATLAWGVNLPAHLVVIKGTEYFDGK 1682
            .:.:..||    |||||..::|..:|..|....:::||||:||:.||||||..|:|: :..|.||
  Fly   539 AITYACAF----HHAGLTTEERDIIEASFKAGALKVLVATSTLSSGVNLPARRVLIR-SPLFGGK 598

  Fly  1683 VKKYVDMPITDVLQMMGRAGRPQFDNEGVAVVLVHDEKKNFYKKFLYDPF-PVESSLLGVLPEHI 1746
                 .|......||:|||||...|..|.::::.::......:..:.... |:.|.|......|:
  Fly   599 -----QMSSLTYRQMIGRAGRMGKDTLGESILICNEINARMGRDLVVSELQPITSCLDMDGSTHL 658

  Fly  1747 N---AEIVAGTVQSKQAALDYLTWTYFFRRLLRNPSYYQLQDIEPEN------VNNFMSNLV--- 1799
            .   .|:::..|.:.:..:|:    :....||.....:..::..|:.      :|:.:..||
  Fly   659 KRALLEVISSGVANTKEDIDF----FVNCTLLSAQKAFHAKEKPPDEESDANYINDALDFLVEYE 719

  Fly  1800 ----------ERVVYELS--AAACLVE----RDGCLIPTFLGR---------------ISSYYYL 1833
                      |..||..:  .||||..    .||.::...|.:               :.:.|.:
  Fly   720 FVRLQRNEERETAVYVATRLGAACLASSMPPTDGLILFAELQKSRRSFVLESELHAVYLVTPYSV 784

  Fly  1834 SYRTMK-------HFLEDLQPGMNTKKVLLAIADSYEFDQLPVRHNEDKHNEEMAEVSRFRPPSS 1891
            .|:...       |..|.|...|.....|:.:.|::.:..|  |.......::|....||
  Fly   785 CYQLQDIDWLLYVHMWEKLSSPMKKVGELVGVRDAFLYKAL--RGQTKLDYKQMQIHKRF----- 842

  Fly  1892 SWDSSYTKTFLLLQAHFARQSLPNSDYLTDTKSALDNATRVMQAMVDYTAERGWLSTTLVVQQLM 1956
                                      |:......|.|.|.:...:..|...||.|.:...:....
  Fly   843 --------------------------YIALALEELVNETPINVVVHKYKCHRGMLQSLQQMASTF 881

  Fly  1957 QSVIQA-----RWFDGSEFLTLPGVNEDNLDAFLNIPHDDYDYLTLPVLKE 2002
            ..::.|     :|   |....:....:|.|  |..|..|..|.:.:|.|.:
  Fly   882 AGIVTAFCNSLQW---STLALIVSQFKDRL--FFGIHRDLIDLMRIPDLSQ 927

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
obe	NP_650472.2	Helicase_PWI	<247..>284	CDD:436309
		BRR2	485..1025	CDD:440817
		DEXHc_ASCC3_1	486..683	CDD:350778
		SEC63	985..1298	CDD:214744	51/275 (19%)
		BRR2	1334..1859	CDD:440817	137/627 (22%)
		DEXHc_ASCC3_2	1336..1525	CDD:350780	49/193 (25%)
		SEC63	1818..2176	CDD:214744	33/212 (16%)
PolQ	NP_524333.1	BRR2	216..779	CDD:440817	138/632 (22%)
		DNA_pol_A_theta	1668..2053	CDD:176475