Protein Alignment Rh6 and OPN1SW

DIOPT Version :10

• Sequence 1: NP_524368.5
• Gene: Rh6 / 41889
• FlyBaseID: FBgn0019940
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_001372054.1
• Gene: OPN1SW / 611
• HGNCID: 1012
• Length: 345
• Species: Homo sapiens
• Alignment Length: 343
• Identity: 90/343 - (26%)
• Similarity: 168/343 - (48%)
• Gaps: 42/343 - (12%)

  Fly    42 LEPMWFGIIGFVI--AILGTMSLAG---NFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMM-MFTM 100
            :.|:|    .|.:  |.:||:.|.|   |.:|:......|.||.|.|..:||::|..|:: :|::
Human    25 IAPVW----AFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSV 85

  Fly   101 FPPVV--LNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLTATAA 163
            ||..|  .||::   :.|..:|.|.|..|::.|.|:.||:..:|::||.||.|.......::..|
Human    86 FPVFVASCNGYF---VFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHA 147

  Fly   164 VLRLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYF--AKDWWNRSYIIVYSLWVYLTPLLT 226
            :..::..|||....::.|.|||:|::|||...:||.|::  ...:.:.||.....::.::.||..
Human   148 LTVVLATWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSL 212

  Fly   227 IIFSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPYT 291
            |.|||..:::|:.|             ||:.:...|...|| |.:::::.:..:..:...:.||.
Human   213 ICFSYTQLLRALKA-------------VAAQQQESATTQKA-EREVSRMVVVMVGSFCVCYVPYA 263

  Fly   292 IINYAGIFESMHLSPLSTI-CGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCLACGK-----D 350
            ......:....|...|..: ..|.|:|:..:.|||:|...:.:::..:.:    :.|||     .
Human   264 AFAMYMVNNRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMK----MVCGKAMTDES 324

  Fly   351 DLTSDSRTQATAEISESQ 368
            |..|..:|:.:. :|.:|
Human   325 DTCSSQKTEVST-VSSTQ 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	80/300 (27%)
		TM helix 1	49..75	CDD:320207	8/30 (27%)
		TM helix 2	82..108	CDD:320207	9/28 (32%)
		TM helix 3	120..150	CDD:320207	12/29 (41%)
		TM helix 4	161..181	CDD:320207	4/19 (21%)
		TM helix 5	208..237	CDD:320207	8/28 (29%)
		TM helix 6	267..297	CDD:320207	4/29 (14%)
		TM helix 7	306..331	CDD:320207	8/25 (32%)
OPN1SW	NP_001372054.1	7tmA_SWS1_opsin	32..311	CDD:320204	79/295 (27%)
		TM helix 1	33..59	CDD:320204	7/25 (28%)
		TM helix 2	66..93	CDD:320204	9/26 (35%)
		TM helix 3	104..134	CDD:320204	12/29 (41%)
		TM helix 4	145..167	CDD:320204	5/21 (24%)
		TM helix 5	194..224	CDD:320204	8/29 (28%)
		TM helix 6	239..269	CDD:320204	5/30 (17%)
		TM helix 7	279..304	CDD:320204	8/24 (33%)