DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6171 and Aplf

DIOPT Version :9

Sequence 1:	NP_001097801.1	Gene:	CG6171 / 41872	FlyBaseID:	FBgn0026737	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_008761298.1	Gene:	Aplf / 500247	RGDID:	1565557	Length:	510	Species:	Rattus norvegicus

Alignment Length:	225	Identity:	72/225 - (32%)
Similarity:	103/225 - (45%)	Gaps:	39/225 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 VKSEEPVASIKDETNPEVPM-KIKAEPVENADEPTSTTPAIKIKAE-----PADNGNSPAAAMVK 97
            ||:.:...:|..|...|.|. |...:|..|..:.|.:.|..:...:     ....|..|.::...
  Rat   292 VKANKLSDTISAEELGEAPKHKAVTKPTTNDKDKTMSHPKCRAGVQSKTFLEKSQGCHPESSSAP 356

  Fly    98 TEPTNSNAQDA------ADESTVSSSSIRTSCRFGIRCYRRNPAHRSAEAHPGDQDYRRPNFPAP 156
            :.|..|:...|      ::||.|.    ||||.:|..|||:||.|....:||||.||..  .|..
  Rat   357 SSPGASHTDTADSVLGCSEESKVR----RTSCMYGANCYRKNPLHFQHFSHPGDSDYGA--VPVT 415

  Fly   157 PLGT----PACPFGNACYRRNPVHFQDYSHPADFNSAQNIRNRLRQRRAQRQNDDDSG----TDE 213
            ..|.    |.||:|.:|||:||.|..:|.|.|           |..|.|..::|||.|    :|:
  Rat   416 DEGVTGDRPECPYGASCYRKNPQHRMEYRHSA-----------LPARVAVDEDDDDVGQPSDSDK 469

  Fly   214 EDEPFGGDNDRDADYRPGADINEDED-DEL 242
            ::|.: ...|.|:|::||.|..|.|| |||
  Rat   470 DEEDY-APTDEDSDWQPGKDDEEKEDVDEL 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6171	NP_001097801.1	zf-CCHH	122..142	CDD:287283	9/19 (47%)
CG6171	NP_001097801.1	zf-CCHH	161..182	CDD:287283	11/20 (55%)
Aplf	XP_008761298.1	FHA	4..102	CDD:238017
		zf-CCHH	383..403	CDD:287283	9/19 (47%)
		zf-CCHH	424..445	CDD:287283	11/20 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334339
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_290VG
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008022
OrthoInspector	1	1.000	-	-		oto98681
orthoMCL	1	0.900	-	-		OOG6_108760
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.640