DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6171 and aplf

DIOPT Version :9

Sequence 1:	NP_001097801.1	Gene:	CG6171 / 41872	FlyBaseID:	FBgn0026737	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001353181.1	Gene:	aplf / 101884102	ZFINID:	ZDB-GENE-111123-1	Length:	475	Species:	Danio rerio

Alignment Length:	262	Identity:	67/262 - (25%)
Similarity:	103/262 - (39%)	Gaps:	50/262 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSATDASTADSGAKRKSSEDITHNCNANFGAENGLRKRVKS---EEPVASIKDETNP----EVPM 58
            ||:.:....|...|||:                   ||:||   ||.:..:.|.|.|    .||.
Zfish   225 MSSEEEELEDKTPKRKT-------------------KRLKSDSEEESLPPLDDATAPSGESSVPD 270

  Fly    59 KIKAEPVENADEPTSTTPAIKIKAEPADNGNSPAAAMVKTEPTNSN--AQDAADESTVSSSSI-- 119
            .:....|...::........:.:..|.|...:   :..:||..:.:  ::..:..|.|:.|.|
Zfish   271 GVNGTGVMERNDEERKGGGRRAQVRPGDQAQN---SKTQTEDRSDSQVSRGLSQRSDVTESEIKT 332

  Fly   120 ---------RTSCRFGIRCYRRNPAHRSAEAHPGDQDYRRPNFPAPPL---GTPACPFGNACYRR 172
                     ||:|.:|..|||:||.|....:||||.||..........   ..|.||:|..|||:
Zfish   333 SRSEVKKPRRTACPYGSSCYRKNPLHFQECSHPGDIDYEEEKADEEENEDDDRPECPYGTQCYRK 397

  Fly   173 NPVHFQDYSHPADFNSAQNIRNRLRQRRAQRQNDDDSGTDEEDEPFGGDNDRDADYRPGADINED 237
            ||:|.::|.|     :....:|......|....|....:...||....:.|.|:||.|.:|.:..
Zfish   398 NPLHKKEYKH-----TKSPPKNTAAAAAADEDEDQYENSFINDESEEEEVDEDSDYVPESDGSGK 457

  Fly   238 ED 239
            ||
Zfish   458 ED 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6171	NP_001097801.1	zf-CCHH	122..142	CDD:287283	8/19 (42%)
CG6171	NP_001097801.1	zf-CCHH	161..182	CDD:287283	11/20 (55%)
aplf	NP_001353181.1	FHA	18..102	CDD:238017
		Rho	149..>324	CDD:333130	22/120 (18%)
		zf-CCHH	345..367	CDD:313506	10/21 (48%)
		zf-CCHH	388..409	CDD:313506	11/25 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008022
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108760
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900