Protein Alignment Atg4b and atg4a

DIOPT Version :10

• Sequence 1: NP_650452.1
• Gene: Atg4b / 41868
• FlyBaseID: FBgn0038325
• Length: 668
• Species: Drosophila melanogaster
• Sequence 2: NP_001016619.1
• Gene: atg4a / 549373
• XenbaseID: XB-GENE-922674
• Length: 395
• Species: Xenopus tropicalis
• Alignment Length: 308
• Identity: 115/308 - (37%)
• Similarity: 176/308 - (57%)
• Gaps: 32/308 - (10%)

  Fly   269 DFYSRIWMTYRREFPIMNGSNYTSDCGWGCMLRSGQMLFAQGLICHFLGRSWRYDSESQLHSTYE 333
            |..||:|.|||::|..:.|:..:||.|||||||.|||:.||.|||..|||.||::...:....|
 Frog    52 DIVSRLWFTYRKKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICQHLGRDWRWEKHKEHPEEY- 115

  Fly   334 DNMHKKIVKWFGDSSSKSSPFSIHALVRLGEHLGKKPGDWYGPASVSYLLKHALEHAAQENADFD 398
                ::|::.|.|  .|...:|||.:.::|...||..|:|:||.:|:.:||        :.|.||
 Frog   116 ----RQILQCFLD--RKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLK--------KLALFD 166

  Fly   399 ---NISVYVAKDCTIYLQDIEDQCSIPEPAPKPH-VPWQQAKRPQAETTK----TEQQQHWKSLI 455
               :::|||:.|.|:.::||:..|..     :|| ....||...|:..::    :.|...|:.|:
 Frog   167 EWNSLAVYVSMDNTVVIEDIKTMCKY-----QPHSCSMAQAASYQSTWSRCRDASGQSSGWRPLL 226

  Fly   456 VLIPLRLGSDKLNPVYAHCLKLLLSTEHCLGILGGKPKHSLYFVGFQEDRLIHLDPHYCQEMVDV 520
            :::|||||.:.:||||....|........||.|||||.|:.||:||..|.:|:||||..|..||.
 Frog   227 LIVPLRLGINHINPVYVDAFKACFKMPQSLGALGGKPNHAYYFIGFSGDEIIYLDPHTTQTFVDT 291

  Fly   521 NQENFSLHSFHC-KSPRKLKASKMDPSCCIGFYCATKSDFDNFMESVQ 567
            ..::   .::|| |.|..:|...:|||..:||:|..::||||:.|.::
 Frog   292 EDQD---QTYHCQKGPNSMKVLNLDPSVALGFFCKDENDFDNWCEVIE 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg4b	NP_650452.1	Peptidase_C54	263..565	CDD:460915	114/304 (38%)
atg4a	NP_001016619.1	Peptidase_C54	46..333	CDD:460915	114/303 (38%)